Table of Contents Author Guidelines Submit a Manuscript
International Journal of Surgical Oncology
Volume 2011, Article ID 785803, 10 pages
http://dx.doi.org/10.1155/2011/785803
Clinical Study

Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS

1Department of Surgery, New York University Langone Medical Center, New York, NY 10016, USA
2Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
3Department of Pathology, New York University Langone Medical Center, New York, NY 10016, USA
4Department of Biological Statistics and Computational Biology, Cornell University, Jthaca, NY 14853, USA

Received 8 September 2010; Accepted 27 December 2010

Academic Editor: Theodore D. Liakakos

Copyright © 2011 J. H. Wolf et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. R. Fisher, J. Dignam, E. Tan-Chiu et al., “Pathologic findings from the national surgical adjuvant breast project (NSABP) eight-year update of protocol b-17: intraductal carcinoma,” Cancer, vol. 86, no. 3, pp. 429–438, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. NIH consensus conference, “Treatment of early-stage breast cancer,” Journal of the American Medical Association, vol. 265, no. 3, pp. 391–395, 1991. View at Google Scholar
  3. T. T. Law and A. Kwong, “Surgical margins in breast conservation therapy: how much should we excise?” Southern Medical Journal, vol. 102, no. 12, pp. 1234–1237, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. U. Veronesi, B. Salvadori, A. Luini et al., “Conservative treatment of early breast cancer. Long term results of 1232 cases treated with quadrantectomy, axillary dissection, and radiotherapy,” Annals of Surgery, vol. 211, no. 3, pp. 250–259, 1990. View at Google Scholar · View at Scopus
  5. S. J. Schnitt, A. Abner, R. Gelman et al., “The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast- conserving surgery and radiation therapy,” Cancer, vol. 74, no. 6, pp. 1746–1751, 1994. View at Publisher · View at Google Scholar
  6. M. C. Smitt, K. Nowels, R. W. Carlson, and S. S. Jeffrey, “Predictors of reexcision findings and recurrence after breast conservation,” International Journal of Radiation Oncology Biology Physics, vol. 57, no. 4, pp. 979–985, 2003. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Clarke, R. Collins, S. Darby et al., “Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials,” Lancet, vol. 366, no. 9503, pp. 2087–2106, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. M. J. Silverstein, “The University of Southern California/Van Nuys prognostic index for ductal carcinoma in situ of the breast,” American Journal of Surgery, vol. 186, no. 4, pp. 337–343, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. S. E. J. Janes, M. Stankhe, S. Singh, and B. Isgar, “Systematic cavity shaves reduces close margins and re-excision rates in breast conserving surgery,” Breast, vol. 15, no. 3, pp. 326–330, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Keskek, M. Kothari, B. Ardehali, N. Betambeau, N. Nasiri, and G. P. H. Gui, “Factors predisposing to cavity margin positivity following conservation surgery for breast cancer,” European Journal of Surgical Oncology, vol. 30, no. 10, pp. 1058–1064, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. D. Cao, C. Lin, S. H. Woo, R. Vang, T. N. Tsangaris, and P. Argani, “Separate cavity margin sampling at the time of initial breast lumpectomy significantly reduces the need for reexcisions,” American Journal of Surgical Pathology, vol. 29, no. 12, pp. 1625–1632, 2005. View at Google Scholar · View at Scopus
  12. A. F. Jacobson, J. Asad, S. K. Boolbol, M. P. Osborne, K. Boachie-Adjei, and S. M. Feldman, “Do additional shaved margins at the time of lumpectomy eliminate the need for re-excision?” American Journal of Surgery, vol. 196, no. 4, pp. 556–558, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. S. P. Povoski, R. E. Jimenez, W. P. Wang, and R. X. Xu, “Standardized and reproducible methodology for the comprehensive and systematic assessment of surgical resection margins during breast-conserving surgery for invasive breast cancer,” BMC Cancer, vol. 9, article 254, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Rizzo, R. Iyengar, S. G. A. Gabram et al., “The effects of additional tumor cavity sampling at the time of breast-conserving surgery on final margin status, volume of resection, and pathologist workload,” Annals of Surgical Oncology, vol. 17, no. 1, pp. 228–234, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. T. L. Huston, R. Pigalarga, M. P. Osborne, and E. Tousimis, “The influence of additional surgical margins on the total specimen volume excised and the reoperative rate after breast-conserving surgery,” American Journal of Surgery, vol. 192, no. 4, pp. 509–512, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. F. A. Vicini, L. L. Kestin, N. S. Goldstein, K. L. Baglan, J. E. Pettinga, and A. A. Martinez, “Relationship between excision volume, margin status, and tumor size with the development of local recurrence in patients with ductal carcinoma-in-situ treated with breast-conserving therapy,” Journal of Surgical Oncology, vol. 76, no. 4, pp. 245–254, 2001. View at Google Scholar
  17. E. S. Hwang, B. Samli, K. N. Tran, P. P. Rosen, P. I. Borgen, and K. J. Van Zee, “Volume of resection in patients treated with breast conservation for ductal carcinoma in situ,” Annals of Surgical Oncology, vol. 5, no. 8, pp. 757–763, 1998. View at Google Scholar · View at Scopus
  18. E. Rakovitch, J. P. Pignol, W. Hanna et al., “Significance of multifocality in ductal carcinoma in situ: outcomes of women treated with breast-conserving therapy,” Journal of Clinical Oncology, vol. 25, no. 35, pp. 5591–5596, 2007. View at Publisher · View at Google Scholar · View at Scopus