Clinical Study
Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS
(a) Comparison of patients who underwent BCS, BCS-AM, and TM procedures. |
| | BCS | BCS-AM | TM | No. of patients | 201 | 151 | 53 |
| Age (mean) | 58 | 59 | 54 | Age (median) | 58 | 58 | 54 | DCIS grade | | | | Grade I | 17 | 10 | 5 | Grade II | 88 | 53 | 15 | Grade III | 96 | 88 | 33 | DCIS size | | | | <1 cm | 67 | 44 | 9 | 1-2 cm | 37 | 22 | 6 | 2–5 cm | 27 | 19 | 9 | >5 cm | 9 | 1 | 2 | N/A | 61 | 65 | 27 | Necrosis | | | | Yes | 124 | 106 | 40 | No | 77 | 45 | 13 | Calcifications | | | | Yes | 147 | 109 | 37 | No | 53 | 42 | 16 | Multifocality | | | | Yes | 112 | 101 | 34 | No | 89 | 50 | 19 | ER | | | | 71–100% | 112 | 83 | 19 | 41–70% | 8 | 10 | 3 | 11–40% | 5 | 2 | 0 | 0–10% | 29 | 26 | 23 | N/A | 47 | 30 | 8 | PR | | | | 71–100% | 22 | 15 | 8 | 41–70% | 15 | 13 | 5 | 11–40% | 24 | 16 | 4 | 0–10% | 93 | 76 | 28 | N/A | 47 | 31 | 8 | ER/PR | | | | Both 71–100 | 29 | 19 | 8 | Both <10 | 19 | 25 | 19 | Margin** | | | | Positive, <1 mm | 117 | 61* | 1 | 1-2 mm | 23 | 9* | 0 | 3–5 mm | 17 | 17 | 0 | 6–9 mm | 6 | 4 | 0 | ≥10 mm | 37 | 60* | 52 | Re-excision | 129 | 61*** | 2 | Residual DCIS | 65 | 33* | 0 |
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BCS: breast conserving surgery; BCS-AM: BCS plus additional margin; TM: total mastectomy. , total <.0001, .
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(b) Indications for surgery and re-excision, categorized by surgeon. |
| | Surgeon A | Surgeon B | Surgeon C | Surgeon D | Total | % |
| Indication for surgery | | | | | | | Palpable mass | 5 | 10 | 4 | 5 | 24 | 6.8 | Nonpalpable mass | 14 | 0 | 0 | 0 | 14 | 4.0 | Calcifications | 55 | 96 | 59 | 67 | 277 | 78.7 | Mammographic lesion | 53 | 15 | 59 | 70 | 197 | 56.0 | Sonographic lesion | 8 | 0 | 6 | 0 | 14 | 4.0 | MRI lesion | 6 | 11 | 7 | 1 | 25 | 7.1 |
| Surgical procedure | | | | | | | Needle localization | 60 | 85 | 40 | 67 | 252 | 71.6 | Surgery bracket | 10 | 2 | 4 | 0 | 16 | 4.5 |
| Indication for re-excision | | | | | | | DCIS at margin | 6 | 18 | 11 | 13 | 48 | 31.4 | Clearance <1 mm | 22 | 28 | 13 | 16 | 79 | 51.6 | Clearance <2 mm | 9 | 4 | 4 | 2 | 19 | 12.4 | Clearance <3 mm | 5 | 1 | 1 | 0 | 7 | 4.6 |
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