Clinical Study

Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS

Table 3

(a) Comparison of the average total volume of BCS and BCS-AM surgery relative to re-excision surgery.

Re-excision
NoYesPTotal

BCS100.3 (n = 79)77.8 (n = 122) *.06786.6 (n = 201)
BCS-AM127.2 (n = 95)98.7 (n = 56) *.281116.6 (n = 151)

Total114.9 (n = 174)79.6 (n = 178) *.003

**<0.001

AM alone26.3 (n = 95)28.9 (n = 56) *.44424.6 (n = 151)

BCS-AM: all resected tissue, including additional margins. AM alone: volumes of additional margins taken with BCS for BCS-AM samples. The volumes of each category were compared relative to re-excision surgery using the P values from two-sample t-tests with unequal variances. value reflects difference between “yes” and “no” for each listed group. value reflects difference between “total BCS” and “total BCS-AM”.
(b) Comparison of average total volume (cm3) for BCS and BCS-AM surgery relative to re-excision surgery using data only from the positive and close margin (<1 mm ) cohort.

Re-excision
NoYesPTotal

BCS81.5 (n = 19)72.9 (n = 98).77374.3 (n = 117)
BCS-AM97.6 (n = 17)100.961 (n = 44).907100.0 (n = 61)

Total89.0 (n = 36)81.6 (n = 142).713*83.1 (n = 178)
**< 0.079

* P value reflects difference between “yes” and “no” for each listed group. **P value reflects difference between “total BCS” and “total BCS-AM”.