Table of Contents Author Guidelines Submit a Manuscript
International Journal of Surgical Oncology
Volume 2012, Article ID 296829, 7 pages
http://dx.doi.org/10.1155/2012/296829
Review Article

Ductal Carcinoma In Situ: What Can We Learn from Clinical Trials?

1Department of Surgery, Senology Unit, San Giovanni Addolorata Hospital, Via Amba-Aradam 9, 00184 Rome, Italy
2Division of Plastic and Reconstructive Surgery, University Campus Bio-Medico, 00128 Rome, Italy
3Department of Radiotherapy, San Giovanni Addolorata Hospital, 00184 Rome, Italy
4Department of Radiology, San Giovanni Addolorata Hospital, 00184 Rome, Italy

Received 13 December 2011; Accepted 22 February 2012

Academic Editor: Virgilio Sacchini

Copyright © 2012 Lucio Fortunato et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. L. Ernster and J. Barclay, “Increases in ductal carcinoma in situ (DCIS) of the breast in relation to mammography: a dilemma,” Journal of the National Cancer Institute. Monographs, no. 22, pp. 151–156, 1997. View at Google Scholar · View at Scopus
  2. J. K. Bobo, N. C. Lee, and S. F. Thames, “Findings from 752,081 clinical breast examinations reported to a national screening program from 1995 through 1998,” Journal of the National Cancer Institute, vol. 92, no. 12, pp. 971–976, 2000. View at Google Scholar · View at Scopus
  3. J. A. Zujewski, L. C. Harlan, D. M. Morrell, and J. L. Stevens, “Ductal carcinoma in situ: trends in treatment over time in the US,” Breast Cancer Research and Treatment, vol. 127, no. 1, pp. 251–257, 2011. View at Publisher · View at Google Scholar
  4. C. Desantis, R. Siegel, P. Bandi, and A. Jemal, “Breast cancer statistics, 2011,” CA Cancer Journal for Clinicians, vol. 61, no. 6, pp. 409–418, 2011. View at Publisher · View at Google Scholar
  5. A. Mascaro, M. Farina, R. Gigli, C. E. Vitelli, and L. Fortunato, “Recent advances in the surgical care of breast cancer patients,” World Journal of Surgical Oncology, vol. 8, article 5, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. B. Erbas, E. Provenzano, J. Armes, and D. Gertig, “The natural history of ductal carcinoma in situ of the breast: a review,” Breast Cancer Research and Treatment, vol. 97, no. 2, pp. 125–144, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. S. J. Katz, P. M. Lantz, N. K. Janz et al., “Patient involvement in surgery treatment decisions for breast cancer,” Journal of Clinical Oncology, vol. 103, pp. 1137–1146, 2005. View at Google Scholar
  8. G. L. Smith, B. D. Smith, and B. G. Haffty, “Rationalization and regionalization of treatment for ductal carcinoma in situ of the breast,” International Journal of Radiation Oncology Biology Physics, vol. 65, no. 5, pp. 1397–1403, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. K. P. McGuire, A. A. Santillan, and P. Kaur, “Are mastectomies on the rise? A 13-year trend analysis of the selection of mastectomy versus breast conservation therapy in 5865 patients,” Annals of Surgical Oncology, vol. 16, pp. 2682–2690, 2009. View at Google Scholar
  10. N. B. Jones, J. Wilson, L. Kotur, J. Stephens, W. B. Farrar, and D. M. Agnese, “Contralateral prophylactic mastectomy for unilateral breast cancer: an increasing trend at a single institution,” Annals of Surgical Oncology, vol. 16, pp. 2691–2696, 2009. View at Google Scholar
  11. L. J. Solin, A. Fourquet, F. A. Vicini et al., “Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breast,” Journal of Clinical Oncology, vol. 23, pp. 5526–5533, 2005. View at Google Scholar
  12. K. Itakura, J. Lessing, T. Sakata et al., “The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ,” Clinical Breast Cancer, vol. 11, no. 1, pp. 33–38, 2011. View at Publisher · View at Google Scholar
  13. B. Fisher, S. Land, E. Mamounas, J. Dignam, E. R. Fisher, and N. Wolmark, “Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the national surgical adjuvant breast and bowel project experience,” Seminars in Oncology, vol. 28, no. 4, pp. 400–418, 2001. View at Google Scholar · View at Scopus
  14. B. Fisher, J. Costantino, C. Redmond et al., “Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer,” The New England Journal of Medicine, vol. 328, no. 22, pp. 1581–1586, 1993. View at Publisher · View at Google Scholar · View at Scopus
  15. B. Fisher, J. Dignam, N. Wolmark et al., “Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from national surgical adjuvant breast and bowel project B-17,” Journal of Clinical Oncology, vol. 16, no. 2, pp. 441–452, 1998. View at Google Scholar · View at Scopus
  16. EORTC Breast Cancer Cooperative Group, EORTC Radiotheapy, N. Bijker, P. Meijnen et al., “Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of european organisation for research and treatment of cancer randomized phase III trial 10853-A study by the EORTC breast cancer cooperative group and EORTC radiotherapy group,” Journal of Clinical Oncology, vol. 24, no. 21, pp. 3381–3387, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. L. Holmberg, H. Garmo, B. Granstrand et al., “Absolute risk reductions for local recurrence after postoperative radiotherapy after sector resection for ductal carcinoma in situ of the breast,” Journal of Clinical Oncology, vol. 26, no. 8, pp. 1247–1252, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Houghton, “Radiotherapy and tamoxifen in women with completely excised ductal carcinoma in situ of the breast in the UK, Australia, and New Zealand: randomised controlled trial,” The Lancet, vol. 362, no. 9378, pp. 95–102, 2003. View at Publisher · View at Google Scholar
  19. G. A. Viani, E. J. Stefano, S. L. Afonso et al., “Breast-conserving surgery with or without radiotherapy in women with ductal carcinoma in situ: a meta-analysis of randomized trials,” Radiation Oncology, vol. 2, no. 1, article 28, pp. 1–12, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), “Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast,” JNCI Monographs, vol. 41, pp. 162–177, 2010. View at Google Scholar
  21. P. Persichetti, B. Cagli, P. Simone et al., “Implant breast reconstruction after salvage mastectomy in previously irradiated patients,” Annals of Plastic Surgery, vol. 62, no. 4, pp. 350–354, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. P. G. Cordeiro, “Breast reconstruction after surgery for breast cancer,” The New England Journal of Medicine, vol. 359, no. 15, pp. 1590–1601, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. R. S. Falk, S. Hofvind, P. Skaane, and T. Haldorsen, “Second events following ductal carcinoma in situ of the breast: a register-based cohort study,” Breast Cancer Research and Treatment, vol. 129, no. 3, pp. 929–938, 2011. View at Publisher · View at Google Scholar
  24. L. A. Lee, M. J. Silverstein, C. T. Chung et al., “Breast cancer-specific mortality after invasive local recurrence in patients with ductal carcinoma-in-situ of the breast,” American Journal of Surgery, vol. 192, no. 4, pp. 416–419, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Fong, E. D. Kurniawan, A. K. Rose et al., “Outcomes of screening-detected ductal carcinoma in situ treated with wide excision alone,” Annals of Surgical Oncology, vol. 18, no. 13, pp. 3778–3784, 2011. View at Publisher · View at Google Scholar
  26. M. J. Silverstein, M. D. Lagios, S. Groshen et al., “The influence of margin width on local control of ductal carcinoma in situ of the breast,” The New England Journal of Medicine, vol. 340, no. 19, pp. 1455–1461, 1999. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Thomas, A. Evans, J. MacArtney et al., “Radiological and pathological size estimations of pure ductal carcinoma in situ of the breast, specimen handling and the influence on the success of breast conservation surgery: a review of 2564 cases from the Sloane project,” British Journal of Cancer, vol. 102, no. 2, pp. 285–293, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. M. J. Silverstein, “The university of Southern California/Van Nuys prognostic index,” in Ductal Carcinoma in Situ of the Breast, M. J. Silverstein, Ed., pp. 459–473, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 2002. View at Google Scholar
  29. S. Y. Wang, T. Shamliyan, B. A. Virnig, and R. Kane, “Tumor characteristics as predictors of local recurrence after treatment of ductal carcinoma in situ: a meta-analysis,” Breast Cancer Research and Treatment, vol. 127, no. 1, pp. 1–14, 2011. View at Publisher · View at Google Scholar
  30. L. Hughes, M. Wang, D. Page et al., “Five year results of intergroup study E5194: local excision alone (without radiation treatment) for selected patients with ductal carcinoma in situ,” Breast Cancer Research and Treatment, vol. 100, supplement 1, pp. S15–S29, 2006. View at Google Scholar
  31. L. Solin, J. Kurtz, A. Fourquet et al., “Fifteen-year results of breast-conserving surgery and definitive breast irradiation for the treatment of ductal carcinoma in situ of the breast,” Journal of Clinical Oncology, vol. 14, no. 3, pp. 754–763, 1996. View at Google Scholar · View at Scopus
  32. J. S. Wong, C. M. Kaelin, S. L. Troyan et al., “Prospective study of wide excision alone for ductal carcinoma in situ of the breast,” Journal of Clinical Oncology, vol. 24, no. 7, pp. 1031–1036, 2006. View at Publisher · View at Google Scholar · View at Scopus
  33. M. E. Sanders, P. A. Schuyler, W. D. Dupont, and D. L. Page, “The natural history of low-grade ductal carcinoma in situ of the breast in women treated by biopsy only revealed over 30 years of long-term follow-up,” Cancer, vol. 103, no. 12, pp. 2481–2484, 2005. View at Publisher · View at Google Scholar · View at Scopus
  34. L. Wapnir, J. Dignam, B. Fisher et al., “Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS,” Journal of the National Cancer Institute, vol. 103, no. 6, pp. 478–488, 2011. View at Publisher · View at Google Scholar
  35. A. Goldhirsch, J. N. Ingle, R. D. Gerlber et al., “Thresholds for th therapies: highlights of the Saint Gallen International Expert Consensus, on the primary therapy of early breast cancer,” Annals of Oncology, vol. 20, pp. 1319–1329, 2009. View at Google Scholar
  36. M. Silverstein, A. Tetch, M. Lagios et al., “Image-detected breast cancer: state-of-the-art diagnosis and treatment,” Journal of the American College of Surgeons, vol. 209, no. 4, pp. 504–520, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. http://www.nccn.org/professionals/physician_gls/pdf/breast.pdf.
  38. G. F. Schwartz, L. Solin, I. Olivotto, V. L. Ernster, and P. I. Pressman, “The consensus conference on the treatment of in situ ductal carcinoma of the breast, April 22–25, 1999,” Cancer, vol. 68, no. 6, pp. 946–954, 2000. View at Google Scholar
  39. G. Farante, S. Zurrda, V. Galimberti et al., “The management of ductal intraepithelial neoplasia (DIN): open controversies and guidelines of the Istituto Europeo di Oncologia (IEO), Milan, Italy,” Breast Cancer Research and Treatment, vol. 128, no. 2, pp. 369–378, 2011. View at Publisher · View at Google Scholar