Preoperative Erythrocyte Sedimentation Rate Independently Predicts Overall Survival in Localized Renal Cell Carcinoma following Radical Nephrectomy

Table 2

Univariate and multivariate Cox regression analyses of predictors of overall survival (OS).

Variable	Crude HR	95% CI	Adjusted HR	95% CI
ESR^†-Based Risk Categories
Low risk	Reference		Reference
Intermediate risk	3.265	0.993–10.733	4.509^*	0.735–27.649
High risk	8.409	2.740–25.805	18.531^**	2.117–162.228
Age	1.028	0.992–1.065	1.030	0.971–1.093
Gender
Female	Reference		Reference
Male	1.502	0.610–3.697	1.306	0.322–5.298
Race
White	Reference		Reference
Non-white	0.658	0.149–2.896	0.150	0.018–1.243
Stage
1	Reference		Reference
2	1.675	0.195–14.374	0.761	0.050–11.573
3-4	10.077	3.436–29.552	4.685	0.721–30.449
Charlson Comorbidity Index	1.274	1.098–1.480	0.754	0.506–1.123
Grade
1-2	Reference		Reference
3	3.266	0.883–12.076	1.373	0.222–8.493
4	32.595	7.684–138.264	21.902	1.937–247.590
Tumor size	1.176	1.072–1.290	1.001	0.820–1.221

^† Erythrocyte Sedimentation Rate.
^*𝑃=0.033.
^**𝑃<0.001.