Review Article

Investigational Paradigms in Downscoring and Upscoring DCIS: Surgical Management Review

Table 1

The USC/VNPI scoring system.

Van Nuys Prognostic Index
ParameterScore 1Score 2Score 3
Van Nuys ClassificationGroup 1Group 2Group 3
Non high nuclear grade without necrosisNonhigh nuclear grade with necrosisHigh nuclear gradewith or without necrosis
Margins≥10 mm1–9 mm<1 mm
Size<15 mm16–40 mm>40 mm
Age>6040–60<40

Modified from Silverstein; Ductal Carcinoma in situ of the breast 2nd ed. 2002.