Review Article
Radiotherapy after Conservative Surgery in Ductal Carcinoma In Situ of the Breast: A Review
Table 3
The influence of the boost on local control.
| Studies | N. of pts. | Median age (y) | Positive margins % | Necrosis % | Median FU (months) | LR % |
| Omlin et al. [31] | | | | | | | Boost | 150 | 41* | 7 | 32 | 72 | 14** | No boost | 166 | | 4 | 41 | | 28** | Yerushalmi et al. [32] | | | | | | | Boost | 20 | 58 | / | / | 81 | 15 | No boost | 55 | / | / | / | | 12.7 | Julian et al. [33] | | | | | | | Boost | 692 | 53 | 21 | 52 | 168 | 13.8 | No boost | 877 | | 15 | 45 | | 14.3 | Monteau et al. [34] | | | | | | | Boost | 147 | 53 | 50 | 60 | 89 | 9.3∧ | No boost | 55 | | 74 | 64 | | 9.6∧ | Wai et al. [35] | | | | | | | Boost | 144 | 56 | 29 | 46 | 112 | 9* | No boost | 338 | 55 | 12 | 55 | | 6* | Wong et al. [44] | | | | | | | Boost | 79 | 58 | 5 | 56 | 46 | 0 | No boost | 121 | | 0.8 | 49 | | 6 |
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*All < 45 years, **10-year LR, ∧7-year LR, #Reexcision for close (<2 mm) margins. Legend: pts.: patients; (y): years; FU: follow up; LR: local recurrence.
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