International Journal of Surgical Oncology / 2012 / Article / Tab 2

Research Article

Parathyroid Carcinoma: The Importance of High Clinical Suspicion for a Correct Management

Table 2

Main clinical features of patients with parathyroid carcinoma (PC) and atypical adenoma (AA).

Patient 1 (PC)Patient 2 (PC)Patient 3 (PC)Patient 4 (AA)

Age46696454
GenderFMMM
SymptomsRenal +
Bones –
Psychiatric +
Renal +
Bones +
Psychiatric +
Renal +
Bones +
Psychiatric −
Renal −
Bones +
Psychiatric +
Palpable massNoNoYesYes
Calcium (mg/dL)14,013,014,213,2
PTH (pg/mL)898184620475
Type of resectionEn bloc resection with the ipsilateral lobe + paratracheal lymphadenectomy(1) MIVAP
(2) After 3 weeks thyroid loboistmectomy + paratracheal lymphadenectomy
En bloc resection with the ipsilateral lobeEn bloc resection with the ipsilateral lobe
Affected glandLeft superiorLeft superiorLeft inferiorRight inferior
Tumor size2,7 × 1,4 × 2,5 cm1,9 × 1,7 × 1,4 cm3,6 × 2 × 2,7 cm3 × 1,7 × 1,2 cm
OutcomeAlive, no evidence of disease at 60 months of followupAlive, surgically treated lung metastasis, rise in calcium/PTH levels without evidence of recurrence at imaging investigations at 36 months of followupAlive, no evidence of disease at 48 months of followupDied for other disease

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