Comparison of Clinicopathological Characteristics in the Patients with Cardiac Cancer with or without Esophagogastric Junctional Invasion: A Single-Center Retrospective Cohort Study

Table 3

Comparison of lymph node metastasis in patients with gastric cardia cancer, with or without esophageal invasion.

Variable	With esophageal invasion (𝑛=26)	Without esophageal invasion (𝑛=54)	𝑃-value
Overall	19 (73.1%)	16 (29.6%)	<0.001**
Depth of tumor invasion
pT1	2/4 (50.0%)	0/15	0.035*
pT2	2/3 (66.7%)	4/8 (50.0%)	0.576
pT3	9/13 (69.2%)	7/13 (53.8%)	0.344
pT4	6/6 (100%)	5/8 (62.5%)	0.154
Location of lymph node
Cervical LN	0	0	—
Mediastinal LN	2 (7.7%)	0	0.103
Perigastric LN	17 (65.4%)	15 (27.8%)	0.002**
Left paracardial	8 (30.8%)	3 (5.6%)	0.004**
Right paracardial	10 (38.5%)	6 (11.1%)	0.006**
Lesser curvature	12 (46.2%)	12 (22.2%)	0.028*
Greater curvature	4 (15.4%)	2 (3.7%)	0.100
Suprapyloric	0	1 (1.9%)	0.675
Infrapyloric	1 (3.8%)	0	0.325
Left gastric artery	4 (15.4%)	7 (13.0%)	0.508
LN at Celiac trunk	1 (3.8%)	2 (3.7%)	0.698
LN along hepatic artery	2 (7.7%)	1 (1.9%)	0.245
LN along splenic artery	3 (11.5%)	1 (1.9%)	0.098
LN at splenic hilum	3 (11.5%)	0	0.032*

* 𝑃<0.05, **𝑃<0.01.