Tumor Regression Grades: Can They Influence Rectal Cancer Therapy Decision Tree?

Table 4

Comparison between TRG and demographic and clinic variables.

Variables	TRG1 + TRG2	TRG3 + TRG4 + TRG5	𝑝 value
Sex
Male	42 (60%)	45 (65.2%)	.52
Female	28 (40%)	24 (34.7%)
Age
Mean (range)	63.1	66.1	.12
Tumor distance from anal verge
>6 cm	27 (38.5%)	41 (59.4%)	.009
≤6 cm	43 (61.4%)	28 (40.5%)
Clinical stage
II	43 (61.4%)	33 (47.8%)	.11
III	27 (38.5%)	36 (52.1%)
Surgical procedure
SSRR (sphincter saving rectal resection)	40 (57.1%)	48 (69.5%)	.13
APR (abdominoperineal resection) + other (rectal resection without anastomose)	30 (42.8%)	21 (30.4%)
Pathological N-stage
ypN0	61 (87.1%)	36 (52.1%)	.001
ypN+	9 (12.8%)	33 (47.8%)
Pathological T-stage
ypT0 − 2	42 (60%)	7 (10.1%)	<.001
ypT3 + 4	28 (40%)	62 (89.9%)