International Journal of Surgical Oncology / 2013 / Article / Tab 1 / Clinical Study
Are the American Society for Radiation Oncology Guidelines Accurate Predictors of Recurrence in Early Stage Breast Cancer Patients Treated with Balloon-Based Brachytherapy? Table 1 American Society for Radiation Oncology (ASTRO) guidelines.
Characteristic ASTRO CS grouping Suitable Cautionary Unsuitable Age, y ≥60 50–59 <50 Tumor size, cm ≤2 2.1–3.0 >3 T stage T1 T0 or T2 T3-T4 Histology Invasive ductal or other favorable subtypes Invasive lobular or DCIS ≤ 3 cm DCIS > 3 cm ER status Positive Negative NA Grade Any NA NA Margins Negative (≥2 mm) Close (<2 mm) Positive Multifocality, cm ≤2 2.1–3 >3 Multicentricity Unicentric NA Present LVI None Limited/focal Extensive EIC None Yes and tumor size ≤ 3 cm Yes and tumor size > 3 cm Nodal status Negative NA Positive Nodal surgery SLNB or ALND NA None performed BRCA 1/2 mutation Not present NA Present Neoadjuvant therapy Not allowed NA Used
CS: consensus statement, DCIS: ductal carcinoma in situ, ER: estrogen receptor, LVI: lymphovascular invasion, EIC: extensive intraductal component, SLNB: sentinel lymph node biopsy, and ALND: axillary lymph node dissection.