International Journal of Surgical Oncology

Clinical Study

Are the American Society for Radiation Oncology Guidelines Accurate Predictors of Recurrence in Early Stage Breast Cancer Patients Treated with Balloon-Based Brachytherapy?

Table 2

Breakdown of patient cohort by individual clinical and pathologic characteristics stratified by ASTRO CS grouping.


Characteristic	ASTRO CS grouping No. of patients (%)
Characteristic	Suitable	Cautionary	Unsuitable

Age, yrs
≥60	58 (100)	89 (75)	34 (52)
50–59	0 (0)	30 (25)	4 (6)
<50	0 (0)	0 (0)	28 (42)
Unknown^a	0 (0)	0 (0)	0 (0)
Tumor Size, cm
≤2	58 (100)	63 (53)	40 (61)
2.1–3.0	0 (0)	9 (8)	7 (11)
>3	0 (0)	0 (0)	3 (4)
DCIS ≤ 3	0 (0)	47 (39)	14 (21)
DCIS > 3	0 (0)	0 (0)	2 (3)
Unknown^a	0 (0)	0 (0)	0 (0)
Histology
IDC	56 (97)	60 (51)	45 (68)
ILC	0 (0)	9 (8)	5 (8)
DCIS	0 (0)	47 (39)	16 (24)
IDC/ILC	2 (3)	2 (1)	0 (0)
Adenoid cystic	0 (0)	1 (1)	0 (0)
Unknown^a	0 (0)	0 (0)	0 (0)
ER status
Positive	58 (100)	87 (73)	56 (85)
Negative	0 (0)	31 (26)	10 (15)
Unknown^a	0 (0)	1 (1)	0 (0)
Margins
Negative, ≥2 mm	58 (100)	72 (61)	21 (32)
Close, <2 mm	0 (0)	47 (39)	17 (26)
Positive	0 (0)	0 (0)	28 (42)
Unknown^a	0 (0)	0 (0)	0 (0)
Multifocality
None	58 (100)	115 (97)	61 (92)
≤2 cm	0 (0)	4 (3)	3 (5)
2.1 cm–3.0 cm	0 (0)	0 (0)	1 (1.5)
>3 cm	0 (0)	0 (0)	1 (1.5)
Unknown^a	0 (0)	0 (0)	0 (0)
Multicentricity
Unicentric	58 (100)	119 (100)	66 (100)
Multicentric	0 (0)	0 (0)	0 (0)
Unknown^a	0 (0)	0 (0)	0 (0)
LVI
None	54 (93)	107 (90)	52 (79)
Limited/focal	0 (0)	7 (6)	3 (4.5)
Extensive	0 (0)	0 (0)	3 (4.5)
Indeterminate	4 (7)	5 (4)	8 (12)
Unknown	0 (0)	0 (0)	0 (0)
EIC, cm^b
None	58 (100)	70 (97)	47 (94)
≤3	0 (0)	2 (3)	2 (4)
>3	0 (0)	0 (0)	1 (2)
Unknown^a	0 (0)	0 (0)	0 (0)
Nodal status^b
Negative	58 (100)	72 (100)	39 (78)
Positive	0 (0)	0 (0)	7 (14)
None performed	0 (0)	0 (0)	4 (8)
Unknown^a	0 (0)	0 (0)	0 (0)

CS: consensus statement, DCIS: ductal carcinoma in situ, IDC: invasive ductal carcinoma, ILC: invasive lobular carcinoma, ER: estrogen receptor, LVI: lymphovascular invasion, and EIC: extensive intraductal component.
Patients with tumor characteristics characterized as unknown or indeterminate were placed in ASTRO categories based on the other criteria.
Excluding DCIS; cautionary ; unsuitable .