Prognostic Factors and Survival in Patients Treated Surgically for Recurrent Metastatic Uterine Leiomyosarcoma
Table 1
Staging for uterine sarcoma (leiomyosarcomas, endometrial stromal sarcomas, adenosarcomas, and carcinosarcomas).
Stage
Definition
(1) Leiomyosarcoma
I
Tumor limited to uterus
IA
<5 cm
IB
>5 cm
II
Tumor extends to the pelvis
IIA
Adnexal involvement
IIB
Tumor extends to the extrauterine pelvic tissue
III
Tumor invades abdominal tissue (not just protruding into the abdomen)
IIIA
One site
IIIB
>one site
IIIC
Metastases to pelvic and/or para-aortic lymph nodes
IV
IVA
Tumor invades bladder and/or rectum
IVB
Distant metastases
(2) Endometrial stromal sarcomas (ESS) and adenosarcomas*
I
IA
Tumor limited to uterus
IB
Tumor limited to the endometrium/endocervix no myometrial invasion
IC
More than half myometrial invasion
II
Tumor extends to the pelvis
IIA
Adnexal involvement
IIB
Tumor extends to the extrauterine pelvic tissue
Tumor extends to the extrauterine pelvic tissue
III
Tumor invades abdominal tissue (not just protruding into the abdomen)
IIIA
One site
IIIB
>one site
IIIC
Metastases to pelvic and/or para-aortic lymph nodes
IV
IVA
Tumor invades bladder and/or rectum
IVB
Distant metastases
(3) Carcinosarcomas
Carcinomas should be staged as carcinomas of the endometrium
Note: simultaneous tumors of the uterine corpus and ovary/pelvis in association with ovarian/pelvic endometriosis should be classified as independent primary tumors (from [11]).
