Prognostic Factors and Survival in Patients Treated Surgically for Recurrent Metastatic Uterine Leiomyosarcoma

Table 3

Survival variables	Number	2 years	5 years	10 years	𝑃 value
Overall	24	33%	27%	9%
Time to fist recurrence (months)
≥12 months	11	77%	39%	19%	0.0060
<12 months	13	30%	0%	0%
Extent of surgical resection
Complete	16	53%	42%	16%	0.004
R1/R2	8	12%	0%	0%
FIGO stage at diagnosis
I	14	47%	47%	16%	0.010
II/III/IV	10	12%	0%	0%
1 tumor versus ≥2 tumors
1 tumor	12	81%	51%	26%	0.015
≥2 tumors	12	33%	0%	0%
Grade
Low	4	50%	50%	25%	0.140
High	21	29%	22%	11%
Type of procedure
Thoracic only	20	75%	75%	75%	0.890
Nonthoracic	4	26%	0%	0%
Local versus distant recurrence
Local	8	63%	25%	0%	0.600
Distant	16	56%	25%	13%
Adjuvant therapy after initial Dx
None	12	58%	20%	20%	0.425
CT and/or RT	12	58%	25%	0%
Adjuvant therapy after recurrence
None	10	50%	36%	18%	0.565
CT and/or RT	14	70%	13%	13%