Clinical Study
Prognostic Factors and Survival in Patients Treated Surgically for Recurrent Metastatic Uterine Leiomyosarcoma
| | Author, year | Leitao et al., 2002 [22] | Giuntoli et al., 2007 [23] |
This study
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| | Patients | | | | | Number | 41 | 80 | 24 | | Time to 1st recurrence (months) | 15 | 16 | 26 | | Median followup (months) | 25 | 47 | 34 | | Recurrence | | | | | Single tumor | 80% | 80% | 46% | | Multiple tumors | 20% | 20% | 54% | | Local | 41% | 22% | 13% | | Distant | 44% | 58% | 34% | | Both | 15% | 20% | 54% | | Treatment | | | | | Surgery alone | 56% | 35% | 42% | | Surgery + C a/o RT* | 44% | 65% | 58% | | Survival factors | | | | | Time to 1st recurrence | Yes | Yes | Yes | | Complete resection | Yes | Yes | Yes | | Single tumor | NR | Yes | Yes | | FIGO (2009) | NR | NR | Yes | | Response to C a/o RT* | No | Yes | No | | Overall survival | | | | | 2 years | 70% | 55% | 57% | | 5 years | 28% | 25% | 24% | | 10 years | NR | 20% | 12% |
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C: chemotherapy; RT: radiation therapy; NR: not reported.
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