Research Article
Minimising Unnecessary Mastectomies in a Predominantly Chinese Community
Table 2
Summary of demographic, clinicopathologic, and outcome data for study population.
| | Clinicopathologic characteristic | All patients () | BCT () | Mastectomy () | value | | | (%) | | (%) | By need (15) | (%) | By choice (9) | (%) |
| | Age in years | | | | | | | | | | | Median (range) | 48 (28–78) | | | | | | | | | | Mean (SD) | 48.6 (10) | | 47.9 (10) | | 50.1 (8.8) | | | | 0.40 | | Mean (SD) | | | 47.9 (10) | | | | 58.0 (6.9) | | 0.003 | | Ethnicity | | | | | | | | | 0.88 | | Chinese | 114 | (66.7) | 98/114 | (86.0) | 8/114 | (7.0) | 8/114 | (7.0) | | | Malay/Indonesian | 12 | (7.0) | 10/12 | (83.3) | 2/12 | (16.7) | 0/12 | | | | Indian | 11 | (6.4) | 10/11 | (91.0) | 1/11 | (9.0) | 0/12 | | | | Other Asian | 14 | (8.2) | 13/14 | (92.9) | 1/14 | (7.1) | 0/14 | | | | Caucasian | 20 | (11.7) | 16/20 | (80.0) | 3/20 | (15.0) | 1/20 | (5.0) | | | Mode of presentation | | | | | | | | | 0.07 | | Symptomatic tumours | 125 | (73.1) | 103/125 | (82.4) | 13/125 | (10.4) | 9/125 | (7.2) | | | Screen detected lesions | 46 | (26.9) | 44/46 | (95.6) | 2/46 | (4.3) | 0 | | | | All patients | 171 | | 147/171 | (85.9) | 15/171 | (8.8) | 9/171 | (5.3) | | | Tumour size in mm (range) | | | | | | | | | | | Median (range) | 19.0 (3–97) | | 18.0 (3–72) | |
35.0 (4–97) | | 15.9 (3–35) | | | | Mean (SD) | 21.1 (15.4) | | 19.2 (12.1) | | 40.5 (28.0) | | | | 0.000 | | (DCIS included) | | | 19.2 (12.1) | | | | 18.3 (12.9) | | 0.83 | | ≤20 mm | 108 | (63.2) | 100/108 | (92.6) | 4/108 | (3.7) | 4/108 | (3.7) | | | 21–50 mm | 51 | (29.8) | 39/51 | (76.5) | 7/510020 | (13.7) | 4/51 | (7.8) | | | >50 mm | 9 | (5.3) | 6/9 | (66.7) | 3/9 | (33.3) | 0 | | | | T4 | 3 | (1.8) | 2/3 | (66.7) | 1/3 | (33.3) | | | | | Pathologic stage | | | | | | | | | <0.001 | | 0 | 22 | (12.9) | 20/22 | (90.1) | 1/22 | (4.5) | 1/22 | (4.5) | | | I | 70 | (41.0) | 69/70 | (98.6) | 1 | (1.4) | 0 | | | | II | 55 | (32.2) | 46/55 | (83.6) | 4/55 | (7.3) | 5/55 | (9.1) | | | III | 21 | (12.3) | 11/221 | (52.4) | 8/21 | (38.1) | 2/21 | (9.5) | | | IV | 1 | (0.6) | 0 | | 1 | | | | | | Unknown | 2 | (1.2) | 1/2 | | | | 1/2 | | | | Histological type | | | | | | | | | 0.34 | | DCIS | 22 | (12.9) | 20/22 | (91.0) | 1/22 | (4.5) | 1/22 | (4.5) | | | Invasive ductal | 132 | (77.2) | 114/132 | (86.4) | 11/132 | (8.3) | 7/125 | (5.6) | | | Invasive lobular | 7 | (4.1) | 5/7 | (71.4) | 1/7 | (1.4) | 1/7 | (1.4) | | | Other invasive | 10 | (5.8) | 8/10 | (80.0) | 2/10 | (20) | | | | | Grade | | | | | | | | | 0.48 | | DCIS | 22 | (12.9) | 20/22 | (91.0) | 1/22 | (4.5) | 1/22 | (4.5) | | | 1 | 29 | (17.0) | 28/29 | (96.5) | 1/29 | (3.6) | 0 | | | | 2 | 61 | (35.6) | 50/61 | (81.7) | 6/61 | (9.8) | 5/61 | (8.2) | | | 3 | 54 | (31.6) | 44/54 | (81.5) | 7/54 | (13.0) | 3/54 | (5.6) | | | Unknown | 5 | (2.9) | 4/4 | (100) | | | | | | | Neoadjuvant medical therapy | | | | | | | | | <0.001 | | Yes | 25 | (14.6) | 16/25 | (64.0) | 8/25 | (32.0) | 1/25 | (4.0) | | | No | 146 | (85.4) | 131/146 | (89.7) | 7/146 | (4.8) | 8/146 | (4.8) | | | Disease extent | | | | | | | | | 0.97 | | Unifocal | 128 | (74.6) | 110/128 | (85.9) | 11/128 | (8.6) | 7/128 | (5.5) | | Multiple foci at diagnosis | 43 | (25.1) | 34/40 | (85) | 4/40 | (10) | 2/40 | (5) |
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BCT: breast conservation surgery; SD: standard deviation; DCIS: ductal carcinoma in situ.
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