Prognostic Relevance of the Peritoneal Surface Disease Severity Score Compared to the Peritoneal Cancer Index for Colorectal Peritoneal Carcinomatosis
Table 3
Univariate Cox-regression analysis, -stats, and -index of PCI and PSDSS for OS and PFS.
Overall survival (OS)
Progression-free survival (PFS)
E/N
Median OS, month
HR (95% CI)
∧
-stats
-index
E/N
Median PFS, month
HR (95% CI)
∧
-stats
-index
PCI
Per unit increase
18/50
28.8
1.11 (1.03–1.20)
0.005#
—
0.737
33/50
9.4
1.09 (1.03–1.14)
0.001#
—
0.680
0 ⩽ PCI ⩽ 9
4/25
NR
1
0.059
1.033
0.693
10/25
17.6
1
0.004
0.870
0.668
10 ⩽ PCI ⩽ 20
11/20
27.1
3.23 (1.03–10.19)
19/20
7.2
3.45 (1.59–7.49)
PCI > 20
3/5
19.9
4.55 (0.99–20.98)
4/5
7.8
2.85 (0.88–9.27)
PSDSS
Per unit increase
18/50
28.8
1.06 (0.97–1.14)
0.191#
—
0.613
33/50
9.4
1.05 (0.99–1.11)
0.096#
—
0.599
2 ⩽ PSDSS ⩽ 3
0/5
NR
1
0.139
0.686
0.603
0/5
NR
1
0.077
0.652
0.561
4 ⩽ PSDSS ⩽ 7
10/26
28.8
a
18/26
9.4
a
8 ⩽ PSDSS ⩽ 10
2/5
18.5
a
3/5
8.4
a
PSDSS > 10
6/14
34.5
a
12/14
9.4
a
E, events; N, patients; HR, hazard ratio; CI, confidence interval; NR, not reached; PCI, Peritoneal Cancer Index; PSDSS, Peritoneal Surface Disease Severity Score. Not estimable as there were no events in the reference group. ∧Based on log-rank test, unless otherwise specified. #Based on Wald’s test.
