Neoadjuvant Chemotherapy in Locally Advanced and Borderline Resectable Nonsquamous Sinonasal Tumors (Esthesioneuroblastoma and Sinonasal Tumor with Neuroendocrine Differentiation)

Table 6

The influence of different factors on PFS and OS.

Factor	Division	Median PFS in years	2-year PFS	value (log rank test)
Histological type ()	Esthesioneuroblastoma	NR	91.7%	0.094
	SNEC	NR	57.0%
Stage ()	Kadish C	NR	60.0%	0.347
	Kadish D	NR	81.4%
Response ()	CR + PR	NR	77.3%	0.266
	SD + PD	NR	60.0%
Resectability achieved ()	Yes	NR	92.3%	0.015
	No	1.10	50.0%
Upfront status ()	Resectable	NR	100%	0.002
	Unresectable	1.10	45.5%
Factor	Division	Median OS in years	2-year OS	value (log rank test)
Histological type ()	Esthesioneuroblastoma	NR	91.7%	0.169
	SNEC	NR	64.5%
Stage ()	Kadish C	NR	79.6%	0.677
	Kadish D	NR	75.0%
Response ()	CR + PR	NR	82.7%	0.185
	SD + PD	NR	60.0%
Resectability achieved ()	Yes	NR	100.0%	0.016
	No	NR	58.3%
Upfront status ()	Resectable	NR	100%	0.008
	Unresectable	NR	54.5%