Endoscopic Stenting as Bridge to Surgery versus Emergency Resection for Left-Sided Malignant Colorectal Obstruction: An Updated Meta-Analysis

Table 1

Details of randomized clinical trials included in the meta-analysis. ES: emergency surgery; IOCL: intraoperative colonic lavage; NI: not indicated; RCT: randomized controlled trial; SBTS: stent as a bridge to surgery.

Reference	Year; (duration)	Type of study; ( of centres)	Tumor site (SBTS)	Tumor site (ES)	Intervention	of patients (SBTS : ES)	Type of stent	Stent to surgery time
Alcántara et al.	2011; (February 2004 to December 2006)	RCT (1)	Rectosigmoid (1); Sigmoid (11); Descending (1); Splenic flexure (2)	Rectosigmoid (3); Sigmoid (4); Descending (2); Splenic flexure (4)	Stent placement followed by planned 1-stage open surgery versus emergency 1-stage open surgery and IOCL	15 : 13		5–7 days
Arezzo et al.	2016; (March 2008 to November 2015)	RCT (5)	Rectosigmoid (NI) Sigmoid (8) Descending (43) Splenic flexure (5)	Rectosigmoid (NI); Sigmoid (12) Descending (34) Splenic flexure (13)	Stent placement followed by planned open or laparoscopic surgery versus emergency surgery	56 : 59	Not indicated	3–8 days
Cheung et al.	2009; (January 2002 to May 2005)	RCT (1)	Not reported	Not reported	Stent placement followed by planned laparoscopic surgery versus emergency open surgery	24 : 24		<2 weeks
Ghazal et al.	2013; (January 2009 to May 2012)	RCT (1)	Rectosigmoid (12); Sigmoid (14); Descending (4); Splenic flexure (0)	Rectosigmoid (10) Sigmoid (17) Descending (3) Splenic flexure (0)	Stent placement followed by planned 1-stage open surgery versus emergency 1-stage total abdominal colectomy and ileorectal anastomosis	30 : 30	Not indicated	7–10 days
Ho et al.	2012; (October 2004 to February 2008)	RCT (1)	Rectosigmoid (5) Sigmoid (10) Descending (3) Splenic flexure (2)	Rectosigmoid (3) Sigmoid (8) Descending (6) Splenic flexure (2)	Stent placement followed by open surgery versus emergency surgery	20 : 19		1-2 weeks
Pirlet et al.	2011; (December 2002 to October 2006)	RCT (9)	Rectosigmoid (8) Sigmoid (15) Descending (6) Splenic flexure (0) Not available (1)	Rectosigmoid (7) Sigmoid (18) Descending (2) Splenic flexure (3) Not available (0)	Stent placement followed by open surgery versus emergency open surgery	30 : 30	Nitinol	Not reported
van Hooft et al.	2011; (March 2007 to August 2009)	RCT (25)	Not reported	Not reported	Stent placement followed by open surgery versus emergency open surgery	47 : 51		<4 weeks