Early Cervical Cancer: Predictive Relevance of Preoperative 3-Tesla Multiparametric Magnetic Resonance Imaging

Table 2

Adjusted odds ratios with 95% confidence intervals (CI) and associated P values from the logistic regression predicting pathologic category T2b in the 203 study cohort patients.

Clinical characteristics	No. of patients	No. of events( of patients)	Univariable analysis		Multivariable analysis
			UOR (95 CI)	P	AOR (95 CI)	p
Age(y)	203	47(23.2)	1.05(1.02-1.09)	0.001	1.05(1.01-1.09)	0.009
Parity	203	47(23.2)	0.99(0.76-1.31)	0.992
BMI	203	47(23.2)	1.04(0.95-1.13)	0.424
Cesarean section
No	175	42(24)	1	0.476
Yes	28	5(17.9)	0.69(0.25-1.92)
History of at least one normal delivery	203			0.401
No	31	9(29)	1
Yes	172	38(22.1)	0.69(0.29-1.63)
Menopause	203			0.007
No	105	16(15.2)	1
Yes	98	31(31.6)	2.57(1.30-5.09)
Histology				0.374
Squamous	143	31(21.7)	1
Adenocarcinoma	51	15(29.4)	1.51(0.73-3.09)
Adenosquamous	9	1(11.1)	0.45(0.05-3.75)
Grade				0.45
1	28	7(25)	1
2	111	24(21.6)	0.83(0.32-2.18)
3	49	10(20.4)	0.77(0.26-2.31)
Unknown	15	6(40)	2.00(0.52-7.65)
SCC ag(ng/mL)	203	47(23.2)	1.04(1.01-1.06)	0.012
MRI T stage				<0.0001
T1b	103	16(11.5)	1
T2a	10	2(20)	1.92(0.38-9.86)
T2b	54	29(53.7)	8.92(4.23-18.82)
Clinical FIGO stage				<0.0001
IB1	126	20(15.8)	1
IB2	52	19(36.5)	7.41(3.04-16.12)
IIA1	12	3(25)	2.67(0.65-11.03)
IIA2	13	5(38.5)	5.00(1.44-17.41)
MRI tumor size	203	47(23.2)	1.84(1.46-2.32)	<0.0001
MRI pelvic LN involvement				0.013
Negative	171	34(19.9)	1
Positive	32	13(40.6)	2.76(1.24-6.13)
MRI parametrial invasion				<0.0001		0.002
No	146	18(12.3)	1		1
Yes	57	29(50.9)	7.37(3.59-15.08)		3.77(1.62-8.79)
MRI parametrial invasion				<0.0001
Negative	146	17(11.6)	1
Unilateral	46	21(45.7)	6.37(2.95-13.76)
Bilateral	11	9(81.8)	34.15(6.80-171.43)
MRI vaginal involvement				0.60
No	193	44(22.8)	1
Yes	10	3(30)	1.45(0.36-5.85)
MRI uterine corpus invasion				<0.0001		<0.0001
No	162	19(11.7)	1		1
Yes	41	28(68.3)	16.21(7.19-36.57)		9.99(4.11-24.32)