Research Article

Outcome of Cervical Lymph Nodes Dissection for Thyroid Cancer with Nodal Metastases: A Southeast Asian 3-Year Experience

Table 2

Subgroup analysis of those who had recurrence in the 3-year follow-up period.

N = 43Recurrence n (%)OR (95% CI)p
Yes, n=16 (37.2)No, n= 27 (62.8)

Types of LND
Central LND n=82 (25.0)6 (75.0)0.569
Lateral LND n=157 (46.7)8 (53.3)-
Central + Lateral LND n=207 (35.0)13 (65.0)
Histological types
Papillary thyroid cancer n=3011 (36.7)19 (63.3)
Follicular thyroid cancer n=72 (28.6)5 (71.4)-0.755
Anaplastic thyroid cancer n=11 (100.0)0 (0.0)
Medullary thyroid cancer n=52 (40.0)3 (60.0)
TNM Staging
I, n=122 (16.7)10 (83.3)
II, n=21 (50.0)1 (50.0)
III, n=10 (0.0)1 (100.0)-0.047
IVa, n=218 (38.1)13 (61.9)
IVb, n=44 (100.0)0 (0.00)
IVc, n=31 (33.3)2 (66.7)
Tumour margin clearYes n=2910 (34.5)19 (65.5)0.71 (0.19-2.59)0.594
No n=146 (42.9)8 (57.1)
LN margin clearanceYes n = 2811 (39.3)17 (60.7)1.29 (0.35-4.81)0.700
No n=155 (33.3)10 (66.7)
Radioiodine usageYes, n =3013 (43.3)17 (56.7)2.55 (0.58-1.12)0.307
No, n =133 (23.1)10 (76.9)
RadiotherapyYes, n = 84 (50.0)4 (50.0)1.92 (0.41-9.01)0.443
No, n = 3512 (34.3)23 (65.7)
ChemotherapyYes, n = 42 (50.0)2 (50.0)1.79 (0.23-14.08)0.621
No, n = 3914 (35.9)25 (64.1)

LND, lymph node dissection; LN, lymph node; P value calculated using Fisher Exact Test. TNM staging is based on American Joint Committee for Cancer (AJCC) Cancer Staging Manual Seventh Edition [6].