Research Article
The Utility of SOX2 and AGR2 Biomarkers as Early Predictors of Tamoxifen Resistance in ER-Positive Breast Cancer Patients
Figure 2
A case of breast carcinoma in group 2 (tamoxifen resistant) with serum AGR2 level 116 ng/ml showed high SOX2 nuclear expression score 9 (a) and high AGR2 cytoplasmic positivity score 8 (b). A case of breast carcinoma in group 3 (tamoxifen resistant) with serum AGR2 level 224 ng/ml showed high SOX2 nuclear positivity score 12 (c) and high AGR2 cytoplasmic positivity score 12 (d) in malignant cells (X100).
(a) |
(b) |
(c) |
(d) |