Research Article
Incidence and Risk Factors of Thyroid Malignancy in Patients with Toxic Nodular Goiter
| Variable | Benign group (n = 77) | Malignant group (n = 21) | value |
| Age (year) | 47.13 ± 11.94 | 48.67 ± 10.66 | 0.594 | Gender | Male | 12 (15.58%) | 8 (38.1%) | 0.023 | Female | 65 (84.42%) | 13 (61.90%) | | Comorbidities | Diabetes mellitus | 9 (11.69%) | 3 (14.29%) | 0.748 | Hypertension | 9 (11.69%) | 4 (19.05%) | 0.378 | Chronic liver disease | 2 (2.6%) | 0 (0%) | 0.456 | Family history of cancer thyroid | 1 (1.3%) | 0 (0%) | 0.600 | Preoperative diagnosis | TMNG | 44 (57.14%) | 17 (80.95%) | 0.046 | STN | 33 (42.86%) | 4 (19.05%) | | Size of the dominant nodule (mm) by the US | 32.29 ± 12.93 | 35.67 ± 14.43 | 0.303 |
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