Brain metastases are a significant cause of morbidity and mortality in patients with systemic cancer. Longer survival times for patients with cancer as a result of early diagnosis and more effective treatment regimens and an aging patient population have resulted in an increase in reported incidence. Advances in neuroimaging techniques and more frequent studies for staging purposes that now include the central nervous system have increased the number of patients diagnosed with brain metastases.

Recent developments in treatment techniques and multimodal management approaches have impacted short- and long-term patient outcomes.

We invite investigators to contribute original research articles as well as review articles that will provide deeper understanding of the current trends in the treatment of brain metastases and the adequacy of various available techniques, particularly surgical ones, for the management of this disease, with special consideration of tumor histology, volume, location in the brain, and other important patient and tumor characteristics. Potential topics include, but are not limited to:

• The technical aspects of surgical resection
• New surgical adjuncts (e.g., interstitial laser ablation)
• Nonsurgical treatment (e.g., radiosurgery)
• Trends in treatment of brain metastases
• Complications associated with the surgical treatment of brain metastases
• The impact of different histologies on surgical outcome (e.g. radio- versus nonradioresistant metastases)
• Expectations from care and quality of life following treatment for brain metastases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijso/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: