Atherogenic Factors and Their Epigenetic Relationships

Figure 1

The basic chromatin unit or nucleosome consists of a protein octamer containing two molecules of each histone (H2A, H2B, H3 and H4), around which DNA is wrapped. The arrangement of nucleosomes can be altered by posttranscriptional modification of histones, that could be associated to heterochromatin, highly compacted silenced chromatin, or euchromatin, transcriptionally active open chromatin.