Vascular Complications following Isolated Limb Perfusion for Local Recurrence of Extremity Melanoma: A Case Report and Literature Review

Table 1

Incidence of vascular complications after HILP in the literature.

Reference	Arterial thrombosis	Thrombosis site	HILP drugs
Rochlin (1965)	2/200 (1%)	Femoral artery	Melphalan
Fontaine (1974)	1/56 (1.8%)	External iliac artery	Melphalan
Bulman (1980)	4/75 (5.3%)	Femoral artery	Melphalan
Krementz (1994)	6/703 (0.9%)	Femoral artery	Drug combinations
Hohenberger (1994)	3/342 (0.9%)	External iliac artery	Drug Combinations
Klicks (1998)	10/466 (2.1%)	External iliac artery	TNF-α + Melphalan
Rossi (2004)	1/20 (5%)	Femoral artery	TNF-α + Melphalan
Grunhagen (2005)	1/217 (0.5%)	Mesenteric artery	TNF-α + Melphalan