Research Article
Layperson-Oriented versus Clinical-Based Models for Assessing 10-Year Incidence of Coronary Heart Disease: National FINRISK Study
Table 3
Regression coefficients (
) and hazard ratio (HR) for incident coronary heart disease estimated based on different Cox models.
| | Men () | Women () | | | HR (95% CI) | | HR (95% CI) |
| Laboratory based | | | | | Age*, year | 3.893 | 49.07 (35.25–68.32) | 4.972 | 144.38 (78.41–265.82) | Current smoking | 0.579 | 1.78 (1.58–2.01) | 0.930 | 2.53 (2.04–3.15) | History of diabetes | 0.950 | 2.59 (1.99–3.36) | 1.185 | 3.271 (2.33–4.59) | History of hypertension | 0.207 | 1.23 (1.06–1.42) | 0.536 | 1.71 (1.41–2.06) | Incapable of walking 500 meters | 0.429 | 1.54 (1.17–2.01) | 0.586 | 1.80 (1.32–2.45) | Parent(s) with myocardial infarction | 0.223 | 1.25 (1.10–1.42) | 0.438 | 1.55 (1.30–1.85) | Systolic blood pressure*, mmHg | 1.491 | 4.44 (2.74–7.21) | 1.933 | 6.91 (3.66–13.05) | Cholesterol to HDL-C ratio* | 1.078 | 2.94 (2.43–3.55) | 0.998 | 2.71 (2.08–3.54) | Baseline survival function at 10 years | | | | | Cohort 1982 | 0.978 | | 0.997 | | Cohort 1987 | 0.979 | | 0.996 | | Cohort 1992 | 0.981 | | 0.997 | | Cohort 1997–2002 | 0.984 | | 0.996 | |
| Non-laboratory based | | | | | Age*, year | 4.012 | 55.23 (39.76–76.73) | 5.256 | 191.79 (104.26–352.80) | Current smoking | 0.630 | 1.88 (1.66–2.12) | 0.956 | 2.60 (2.10–3.23) | History of diabetes | 0.952 | 2.59 (1.99–3.36) | 1.282 | 3.60 (2.59–5.02) | History of hypertension | 0.219 | 1.24 (1.07–1.44) | 0.575 | 1.78 (1.47–2.14) | Incapable of walking 500 meters | 0.480 | 1.62 (1.23–2.12) | 0.539 | 1.71 (1.25–2.35) | Parent(s) with myocardial infarction | 0.258 | 1.29 (1.13–1.47) | 0.402 | 1.49 (1.25–1.78) | Systolic blood pressure*, mmHg | 1.436 | 4.20 (2.59–6.84) | 1.919 | 6.81 (3.61–12.87) | Body mass index, kg/m2 | 0.951 | 2.59 (1.65–4.05) | 0.732 | 2.08 (1.26–3.44) | Baseline survival function at 10 years | | | | | Cohort 1982 | 0.974 | | 0.996 | | Cohort 1987 | 0.977 | | 0.995 | | Cohort 1992 | 0.980 | | 0.997 | | Cohort 1997–2002 | 0.984 | | 0.996 | |
| Layperson oriented | | | | | Age*, year | 4.219 | 68.00 (49.20–93.98) | 5.739 | 310.77 (172.55–559.70) | Current smoking | 0.642 | 1.90 (1.68–2.14) | 0.929 | 2.53 (2.04–3.14) | History of diabetes | 0.937 | 2.55 (1.96–3.31) | 1.296 | 3.65 (2.62–5.10) | History of hypertension | 0.303 | 1.35 (1.17–1.57) | 0.722 | 2.06 (1.71–2.47) | Incapable of walking 500 meters | 0.462 | 1.59 (1.21–2.08) | 0.491 | 1.63 (1.19–2.24) | Parent(s) with myocardial infarction, | 0.266 | 1.30 (1.14–1.49) | 0.386 | 1.47 (1.23–1.75) | Body mass index, kg/m2 | 1.147 | 3.15 (2.02–4.91) | 0.887 | 2.43 (1.47–4.02) | Baseline survival function at 10 years | | | | | Cohort 1982 | 0.973 | | 0.996 | | Cohort 1987 | 0.977 | | 0.995 | | Cohort 1992 | 0.980 | | 0.997 | | Cohort 1997-2002 | 0.985 | | 0.996 | |
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*Natural logarithm of the continuous variables.
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