Effect of Preoperative N-Acetylcysteine on Postoperative Blood Loss Parameters in Cardiac Surgery Patients

Table 2

Preoperative (Pre-op) characteristics.

Endpoint	N-acetylcysteine group (𝑛=79)	Control group (𝑛=106)	P Value
Days between cath and surgery	2.05 ± 1.2	1.91 ± 1.1	.398
Precath Scr (mg/dL)	1.7 ± 1.5	1.2 ± 0.3	<.005
Preop Scr (mg/dL)	1.6 ± 1.4	1.2 ± 0.4	.002
Preop PT time (secs)	10.7 ± 1.1	10.5 ± 0.9	.284
Preop Hgb (g/dL)	12.3 ± 1.6	13.2 ± 2.0	.001
Preop Hct (%)	36.6 ± 4.3	39.2 ± 5.2	<.005
Preop platelets (×10^3 mm^3)	201 ± 54	209 ± 66	.372
Received precath hydration ≥ 75 mL/hr	22	25
Received precath bicarb	5	2
Received precath hydration and bicarb	1	0

Cath: catheterization.
Scr: serum creatinine.
PT: prothrombin time.
Hgb: hemoglobin.
Hct: hematocrit.