Research Article
Effect of Preoperative N-Acetylcysteine on Postoperative Blood Loss Parameters in Cardiac Surgery Patients
Table 4
Secondary Endpoints.
| | Endpoint | N-acetylcysteine group () | Control group () | P Value |
| | First postop PT time (secs) | 15.9 ± 3.2 | 16.6 ± 3.6 | .196 | | Lowest Hgb in first 24 hrs (g/dL) | 8.4 ± 1.3 | 8.8 ± 1.6 | .088 | | Lowest Hgb in second 24 hrs (g/dL) | 8.7 ± 1.1 | 8.9 ± 1.1 | .227 | | Lowest Hgb in third 24 hrs (g/dL) | 9.0 ± 1.0 | 9.2 ± 1.0 | .132 | | Lowest Hct in first 24 hrs (%) | 25.0 ± 3.7 | 26.0 ± 4.7 | .075 | | Lowest Hct in second 24 hrs (%) | 25.9 ± 3.3 | 26.6 ± 3.3 | .161 | | Lowest Hct in third 24 hrs (%) | 26.8 ± 3.2 | 27.6 ± 3.2 | .100 | | Lowest platelet count in first 24 hrs (×103/mm3) | 116 ± 43 | 114 ± 35 | .735 | | Lowest platelet count in second 24 hrs (×103/mm3) | 122 ± 44 | 116 ± 39 | .283 | | Lowest platelet count in third 24 hrs (×103/mm3) | 139 ± 50 | 127 ± 49 | .121 | | Number of postop transfusions | 2.2 ± 2.5 | 2.3 ± 2.4 | .653 | | Postop hospital stay (days) | 8.8 ± 8.8 | 7.6 ± 5.1 | .252 |
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PT: prothrombin time.
Hgb: hemoglobin.
Hct: hematocrit.
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