Vascular Homeostasis and Angiogenesis Determine Therapeutic Effectiveness in Type 2 Diabetes

Table 2

A predominant role of VEGFR2 correlates with PTCF reduction in late stage of DN.

	Vascular homeostasis				Renal hemodynamics
	Early DN	𝑃value	Normal		Early DN	𝑃value	Normal
VEGF R1 ng/mL	60±12	NS	49 ± 5	PTCF mL/min/1.73m^2	379 ± 70	<.05	483 ± 43
VEGF R2 ng/mL	5715 ± 1400	NS	6126 ± 1066
	Late DN	𝑃value	Normal		Late DN	𝑃value	Normal
VEGF R1 ng/mL	33 ± 17	<.01	55 ± 11	PTCF mL/min/1.73m^2	277 ± 80	<.001	483 ± 43
VEGF R2 ng/mL	10414 ± 2198	<.01	7696 ± 1892