(a)

(b)

(c)

Figure 3: Effects of CNP on Ang II-induced myocardial interstitial fibrosis. (a) Representative images of Masson’s trichrome (MT) staining of heart sections. Scale bars: 100 μm. (b) Quantitative analysis of myocardial interstitial fibrosis in vehicle- and CNP-treated mice 2 weeks after saline or Ang II infusion. (c) Collagen I and III transcript expression in vehicle- and CNP-treated mice 2 weeks after saline or Ang II infusion. Results are mean ± SEM (–9 each). *.