Research Article

Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages

Table 1

Biochemical characterization of chylomicron remnant-like lipid particles (CRLP) incubated without (CRLPw/o) or with plasma (CRLP+). Total cholesterol (TCH), triacylglycerol (TG), and free cholesterol (FCH) are expressed as means ± SD (n).

TCHTGFCHTG/TCHFCH/TCH
(mM)(mM)(mM)(molar ratio)(molar ratio)

CRLPw/o0.87 ± 0.57 (20)**8.41 ± 2.90 (20)0.45 ±0.21 (7)9.68 ± 2.88 (20)**0.52 ± 0.30 (7)*
CRLP+1.79 ± 0.88 (5)7.42 ± 3.79 (5)0.38 ± 0.20 (5)4.95 ± 2.30 (5)0.21 ± 0.11 (5)

* P < 0.05 versus CRLP+
** P < 0.005 versus CRLP+.