Research Article

Dual AAV/IL-10 Plus STAT3 Anti-Inflammatory Gene Delivery Lowers Atherosclerosis in LDLR KO Mice, but without Increased Benefit

Figure 6

Analysis of the aortic wall thickness by HRUS. HRUS was used to measure the wall thickness of the aorta. (a) shows quanitification of the thoracic region of the aortas in 3–5 animals from each animal group. Note that the hSTAT3-, hIL-10-, and hSTAT3-plus-hIL-10-treated animals had thinner wall thicknesses than the Neo-treated animals, indicating significant efficacy. (b) shows quantification of the renal region of the aortas in 3–5 animals from each animal group.
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(a)
524235.fig.006b
(b)