International Journal of Vascular Medicine / 2012 / Article / Tab 2

Research Article

A Diet Enriched in Docosahexanoic Acid Exacerbates Brain Parenchymal Extravasation of Apo B Lipoproteins Induced by Chronic Ingestion of Saturated Fats

Table 2

Effects of various feeding regimens on plasma lipids in wild-type (C57BL/6J) mice.

SFA 5 m+LF 2 m+DHA 2 m

TG (mM)0.39 ± 0.040.54 ± 0.03*0.43 ± 0.04
TC (mM)1.45 ± 0.231.69 ± 0.173.11 ± 0.12**
NEFA (mEq/L)0.42 ± 0.030.45 ± 0.030.53 ± 0.05
Body weight
 Final25.65 ± 0.6423.72 ± 0.9620.21 ± 0.50**
 Weight gain8.41 ± 0.515.7 ± 1.123.3 ± 0.51**

Plasma total cholesterol (TC), triglycerides (TGs), and non-esterified fatty acids (NEFAs) were measured at the end of the feeding regimen in mice fed saturated fats (SFA 5 m) and SFA-fed mice switched to an LF (+LF 2 m) and DHA diet (+DHA 2 m). Final body weight and weight gain were also calculated. Data represented as mean ± standard error of mean. Means were compared with one-way ANOVA, where considered statistically significant (*).

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