Vascular Reactivity Concerning Orthosiphon stamineus Benth-Mediated Antihypertensive in Aortic Rings of Spontaneously Hypertensive Rats

Table 1

Maximal contractile (𝐸_max) responses and sensitivity (pD₂) for PE intact- and PE denude-induced contraction’s in aortic rings.

Group	PE intact		PE denude
	𝐸max (g)	pD2 (−log EC50)	𝐸max (g)	pD2 (−log EC50)
Control (vehicle)	0.90±0.10	6.67±0.31	0.43±0.04	7.73±0.32
Losartan (10 mg /kg)	0.35±0.03^∗	6.84±0.22	0.43±0.02	8.39±0.19
WOS (1000 mg/kg)	0.30±0.06^∗	7.05±0.62	0.39±0.02	7.72±0.18
WMOS (1000 mg/kg)	0.33±0.03^∗	7.24±0.22	0.57±0.02^∗	7.72±0.10

Each value represents the mean ± SEM of 5 to 8 SHRs. *Denotes 𝑃<0.05 compared to control for each drug.