Influence of Peripheral Artery Disease and Statin Therapy on Apolipoprotein Profiles

Table 2

Lipid measures of subjects with peripheral artery disease (PAD) and controls. Values are means (standard deviation).

Variables	Control group (𝑛=39)	PAD no statin group (𝑛=12)	PAD statin group (𝑛=17)	ANCOVA 𝑃 value	ΔAdjusted mean = control group − PAD groups	ΔAdjusted mean = PAD no statin group − PAD statin group
Triglycerides (mg/dL)	87.5 (41.9)	154.1 (116.9)	133.9 (92.3)	0.011	−60.6**	21.6
Total cholesterol (mg/dL)	181.5 (53.2)	177.8 (31.3)	157.1 (32.3)	0.062	23.4*	17.4
HDL-C (mg/dL)	52.4 (15.2)	44.3 (13.6)	46.8 (13.7)	0.016	10.7*	−3.9
LDL-C (mg/dL)	117.5 (38.6)	108.3 (28.0)	87.2 (26.6)	0.011	23.3**	20.2
LDL-C/HDL-C	2.35 (0.83)	2.65 (1.22)	1.92 (0.64)	0.078	−0.1	0.77*
Non-HDL-C (mg/dL)	129.1 (47.8)	133.5 (32.9)	110.3 (27.9)	0.158	12.6	21.3
Total cholesterol/HCL-C ratio	3.62 (1.10)	4.36 (1.60)	3.56 (1.04)	0.076	−0.5	0.86
Triglyceride/HDL-C ratio	1.93 (1.48)	4.19 (3.78)	3.50 (3.35)	0.005	−2.3***	0.82

^∗𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001.
HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.