Relation of Serum Leptin and Adiponectin Level to Serum C-Reactive Protein: The INTERLIPID Study
Table 2
BMI, SBP, serum leptin, adiponectin, and other characteristics by quartile of serum CRP in women.
Variable
Quartile 1
Quartile 2
Quartile 3
Quartile 4
Trend
CRP range (mg/L)
0.054–0.211
0.230–0.494
0.505–1.150
1.160–7.400
Number ()
48
48
49
48
Hawaii (%)
12.5
35.4
61.2
75.0
<0.001
Age (y)
48.4 ± 5.9
49.8 ± 5.9
50.3 ± 5.7
49.5 ± 4.7
0.274
Cigarettes/day
0.2 ± 1.0
0
0.4 ± 2.9
0.5 ± 2.9
0.324
PA index
4.8 ± 4.5
3.6 ± 3.8
2.3 ± 3.7
2.1 ± 3.2
<0.001
SBP (mmHg)
114 ± 12
114 ± 12
117 ± 14
119 ± 14
0.024
HbA1c (%)
4.4 ± 0.3
4.6 ± 0.5
4.6 ± 0.4
4.8 ± 0.9
<0.001
BMI (kg/m2)
21.9 ± 1.8
23.4 ± 2.4
24.8 ± 3.5
26.9 ± 5.4
<0.001
Leptin (mcg/L)*
5.5 (4.4, 8.4)
7.8 (6.2, 10.5)
11.1 (7.9, 15.3)
14.0 (8.1, 18.8)
<0.001
Adiponectin (mg/L)*
13.1 (8.9, 18.7)
10.7 (7.7, 15.1)
10.4 (7.6, 12.8)
8.5 (5.4, 10.4)
<0.001
Data are shown as mean ± SD or median (25 percentile, 75 percentile). PA index: physical activity index score; SBP: systolic blood pressure; HbA1c: hemoglobin A1c; BMI: body mass index; site (Hawaii = 1, Japan = 0).