Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population
Table 1
Main demographic and clinical characteristics of patients with abdominal thrombosis (AT) and healthy controls (HC). Portal vein thrombosis (PVT) and Budd-Chiari syndrome (BCS) patient characteristics are separately reported.
(A) PVT (%)
(B) BCS (%)
(A) + (B) AT (%)
HC (%)
Number of patients
54 (100)
31 (100)
85 (100)
150 (100)
Age: median
53
46
51
53
Male sex
28 (51.9)
14 (45.0)
42 (49.4)
71 (47.3)
Mesenteric and/or splenic vein thrombosis
15 (27.8)
5 (16.1)
20 (23.5)
—
Cava vein thrombosis
0 (0)
7 (22.6)
7 (8.2)
0 (0)
Esophageal varices:
16/14/24
12/6/13
28/20/37
—
large-medium/small/absent
(29.6)/(25.9)/(44.5)
(38.7)/(19.4)/(41.9)
(32.9)/(23.6)/(43.5)
Bleeding episodes
16 (29.6)
7 (22.6)
23 (27.0)
0 (0)
Thrombosis in other sites
5 (9.3)
6 (19.4)
11 (12.9)
0 (0)
Myeloproliferative neoplasm
20 (37.0)
17 (54.8)
37 (43.5)
0 (0)
Recent abdominal surgery
10 (18.5)
2 (6.4)
12 (14.1)
0 (0)
Oral contraception or pregnancy
6 (11.1)
4 (11.8)
10 (11.8)
0 (0)
Abdominal acute disease
6 (11.1)
1 (3.2)
7 (8.2)
0 (0)
Chronic disease
4 (7.4)
5 (16.1)
9 (10.6)
0 (0)
Not a single disease or clinical status associated