Clinical Study

Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population

Table 1

Main demographic and clinical characteristics of patients with abdominal thrombosis (AT) and healthy controls (HC). Portal vein thrombosis (PVT) and Budd-Chiari syndrome (BCS) patient characteristics are separately reported.

(A) PVT (%)(B) BCS (%)(A) + (B) AT (%)HC (%)

Number of patients54 (100)31 (100)85 (100)150 (100)
Age: median53465153
Male sex28 (51.9)14 (45.0)42 (49.4)71 (47.3)
Mesenteric and/or splenic vein thrombosis15 (27.8)5 (16.1)20 (23.5)
Cava vein thrombosis0 (0)7 (22.6)7 (8.2)0 (0)
Esophageal varices: 16/14/2412/6/1328/20/37
large-medium/small/absent(29.6)/(25.9)/(44.5)(38.7)/(19.4)/(41.9)(32.9)/(23.6)/(43.5)
Bleeding episodes16 (29.6)7 (22.6)23 (27.0)0 (0)
Thrombosis in other sites5 (9.3)6 (19.4)11 (12.9)0 (0)
Myeloproliferative neoplasm20 (37.0)17 (54.8)37 (43.5)0 (0)
Recent abdominal surgery10 (18.5)2 (6.4)12 (14.1)0 (0)
Oral contraception or pregnancy6 (11.1)4 (11.8)10 (11.8)0 (0)
Abdominal acute disease6 (11.1)1 (3.2)7 (8.2)0 (0)
Chronic disease4 (7.4)5 (16.1)9 (10.6)0 (0)
Not a single disease or clinical status associated8 (14.8)2 (6.4)10 (11.8)0 (0)