Inhibition of Angiogenesis In Vitro by Chebulagic Acid: A COX-LOX Dual Inhibitor

Figure 6

Effect of CA on the distribution of 𝛽 catenin. HUVECs maintained in culture in MCDB 131 medium containing 10% FBS were supplemented with 25 μM CA. The level of 𝛽 catenin in the nucleus and cytosol at 24 and 48 hours was estimated by ELISA using anti-𝛽 catenin antibody (1 : 1000) and expressed as percent of total. CS 24 and CS 48: control at 24 and 48 hours. CAS 24 and CAS 48: chebulagic acid at 24 and 48 hours.