Clinical Study

Greater Endothelial Apoptosis and Oxidative Stress in Patients with Peripheral Artery Disease

Table 1

Clinical characteristics of subjects with peripheral artery disease (PAD) and controls.

VariablesControl groupPAD group value

Age (years)70 (9)64 (10)0.014
Sex (% men)50490.923
Race (% Caucasian)69450.069
Current smoking (% yes)0400.002
Hypertension (% yes)2589<0.001
Dyslipidemia (% yes)81930.104
Diabetes (% yes)048<0.001
Obesity (% yes)13470.008
Abdominal obesity (% yes)13570.001
Metabolic syndrome (% yes)084<0.001
Weight (kg)74.2 (12.5)84.1 (18.7)0.040
Body mass index (kg/m2)25.5 (3.1)29.6 (5.9)0.006
Ankle/brachial index1.12 (0.06)0.72 (0.25)<0.001
Six-minute walk distance (m)524 (103)337 (96)<0.001
Six-minute walk rating of perceived exertion (score)13.9 (2.1)13.5 (2.4)0.451
Total strides (strides/day)5526 (2381)3306 (1611)<0.001
Average cadence (strides/min)15.9 (3.8)11.7 (2.6)<0.001

Values are means (standard deviation) or percentage of subjects in each group.