Vascular Leakage in Dengue Hemorrhagic Fever Is Associated with Dengue Infected Monocytes, Monocyte Activation/Exhaustion, and Cytokines Production

Table 5

Mean ± SD of the level of interleukin-10 (IL-10) in patients with DF, DHF grades I and II, DSS, and OFIs patients, followed by the day of illness related to fever.

IL-10 (pg/mL)
Type	Day −2	Day −1	Day 0	Day +1	Day +2	Conval^*
DF; ()	44.0 ± 28.8; ()	41.1 ± 22.9^**; ()	56.7 ± 37.5; ()	29.0 ± 14.3; ()	14.4 ± 10.1; ()	1.2 ± 0.7; ()
DHF I; ()	19.4 ± 11.6; ()	93.4 ± 41.8; ()	55.3 ± 32.8; ()	19.7 ± 11.5; ()	8.5 ± 6.3; ()	1.2 ± 1.0; ()
DHF II; ()	52.3 ± 34.9; ()	125.6 ± 60.1; ()	57.8 ± 34.3; ()	25.3 ± 14.4; ()	10.2 ± 7.4; ()	1.1 ± 0.6; ()
DSS; ()	29.1 ± 11.2; ()	153.6 ± 65.0; ()	41.6 ± 25.4; ()	68.5 ± 40.7; ()	16.5 ± 10.7; ()	1.0 ± 0.4; ()
OFIs; ()	2.9 ± 2.0; ()	28.5 ± 15.9^¥; ()	17.9 ± 10.1^‡; ()	8.8 ± 6.6; ()	7.8 ± 3.6; ()	0.8 ± 0.2; ()

Conval^* = Convalescence.
DF versus DHF/DSS: < 0.01; OFIs versus DHF/DSS: ^¥ < 0.05.
OFIs versus dengue (DF + DHF): ^‡ < 0.05; DSS versus DF and OFIs: < 0.05.