International Journal of Vascular Medicine / 2016 / Article / Tab 3

Research Article

New Indices of Endothelial Function Measured by Digital Thermal Monitoring of Vascular Reactivity: Data from 6084 Patients Registry

Table 3

Comparison between CVD risk assessment methods.

MethodType (structural, functional, and risk factors)Independent of agePredictive valueResponse to therapyEase of use and applicability in primary care settingIntra- and interobserver reproducibilitySelf-monitoring by patients at home

Coronary artery calciumStructural+++++++

Carotid IMT and plaqueStructural++++++

Ankle brachial indexStructural+++++++

Arterial stiffness (e.g., PWV, AI, and )Structural/

Risk factor-based risk calculators (e.g., FRS, SCORE, and QRISK2)Risk factors++n/a+++++++


PAT (RHI)Functional++++++++++++

PPG (RI)Functional++++++++++++

DTM (VRI)Functional+++++++++++++

Carotid IMT: carotid intimal-media thickness; PWV: pulse wave velocity; AI: augmentation index; : indices of large and small artery compliance (elasticity); FRS: Framingham Risk Score; SCORE: Systematic Coronary Risk Evaluation risk score system published by the European Society of Cardiology; QRISK2: risk calculator developed by UK National Health Service; FMD: flow-mediated dilatation; PAT: peripheral arterial tonometry; RHI: reactive hyperemia index; PPG: photoplethysmography for digital pulse waveform analysis; RI: reflection index; DTM: digital thermal monitoring; VRI: vascular reactivity index.