Research Article
Investigation of TGFβ1-Induced Long Noncoding RNAs in Endothelial Cells
Table 3
Results of bioinformatics analyses on downregulated pathways in HUVECs after TGF
1 (10 ng/mL) stimulation.
| Pathway analysis | Downregulated gene count | value |
| Olfactory transduction | 405 | 0.0036241 | Apoptosis | 86 | 0.0050919 | PI3K-Akt signaling pathway | 346 | 0.006535 | mRNA surveillance pathway | 91 | 0.0082309 | Ribosome biogenesis in eukaryotes | 85 | 0.0119435 | Circadian rhythm | 30 | 0.0140969 | Chemical carcinogenesis | 80 | 0.0189201 | Ras signaling pathway | 227 | 0.0201366 | Melanoma | 71 | 0.0211199 | Hypertrophic cardiomyopathy (HCM) | 85 | 0.0284512 | Rap1 signaling pathway | 213 | 0.0320182 | Estrogen signaling pathway | 100 | 0.0381713 | Tight junction | 134 | 0.0382214 | Nicotinate and nicotinamide metabolism | 28 | 0.0382726 | Drug metabolism-cytochrome P450 | 68 | 0.0398014 | Serotonergic synapse | 114 | 0.0453301 | Neuroactive ligand-receptor interaction | 321 | 0.0459533 | Tyrosine metabolism | 39 | 0.0463610 |
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