Table of Contents Author Guidelines Submit a Manuscript
International Journal of Vascular Medicine
Volume 2016, Article ID 3107879, 11 pages
Research Article

Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms

1Almazov Federal Medical Research Centre, Akkuratova 2, Saint Petersburg 197341, Russia
2Saint Petersburg State University, Universitetskaya Nab. 7/9, Saint Petersburg 199034, Russia
3ITMO University, Institute of Translational Medicine, 49 Kronverksky Prospekt, Saint Petersburg 197101, Russia
4Institute of Cytology, Russian Academy of Sciences, Tikhoretsky Avenue 4, Saint Petersburg 194064, Russia
5Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Postboks 1171, Blindern, 0318 Oslo, Norway

Received 30 September 2015; Revised 3 December 2015; Accepted 14 December 2015

Academic Editor: John A. Kern

Copyright © 2016 Anna Malashicheva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Elena Ignatieva, Daria Kostina, Olga Irtyuga, Vladimir Uspensky, Alexey Golovkin, Natalia Gavriliuk, Olga Moiseeva, Anna Kostareva, and Anna Malashicheva, “Mechanisms of Smooth Muscle Cell Differentiation Are Distinctly Altered in Thoracic Aortic Aneurysms Associated with Bicuspid or Tricuspid Aortic Valves,” Frontiers in Physiology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Amalia Forte, Ciro Bancone, Gilda Cobellis, Marianna Buonocore, Giuseppe Santarpino, Theodor J.M. Fischlein, Marilena Cipollaro, Marisa De Feo, and Alessandro Della Corte, “A Possible Early Biomarker for Bicuspid Aortopathy: Circulating Transforming Growth Factor β-1 to Soluble Endoglin Ratio,” Circulation Research, vol. 120, no. 11, pp. 1800–1811, 2017. View at Publisher · View at Google Scholar
  • Aline Verstraeten, Ilse Luyckx, and Bart Loeys, “Aetiology and management of hereditary aortopathy,” Nature Reviews Cardiology, vol. 14, no. 4, pp. 197–208, 2017. View at Publisher · View at Google Scholar
  • Aruna Poduripp. 79–84, 2017. View at Publisher · View at Google Scholar
  • Daria Kostina, Dmitry Zverev, Vadim Grebennik, Irina Voronkina, Anna Kostareva, Anna Malashicheva, Mikhail Gordeev, and Elena Ignatieva, “Aortic Graft at Coronary Artery Bypass Surgery as a Source of Human Aortic Smooth Muscle Cells,” Cell Transplantation, vol. 26, no. 10, pp. 1663–1668, 2017. View at Publisher · View at Google Scholar
  • Sebastian Albinsson, Alessandro Della Corte, Azra Alajbegovic, Katarzyna K. Krawczyk, Ciro Bancone, Umberto Galderisi, Marilena Cipollaro, Marisa De Feo, and Amalia Forte, “Patients with bicuspid and tricuspid aortic valve exhibit distinct regional microrna signatures in mildly dilated ascending aorta,” Heart and Vessels, 2017. View at Publisher · View at Google Scholar
  • Magdalena Budzyń, Bogna Gryszczyńska, Wacław Majewski, Zbigniew Krasiński, Magdalena Paulina Kasprzak, Dorota Formanowicz, Krzysztof Wojciech Strzyżewski, and Maria Iskra, “The Association of Serum Thrombomodulin with Endothelial Injuring Factors in Abdominal Aortic Aneurysm,” BioMed Research International, vol. 2017, pp. 1–10, 2017. View at Publisher · View at Google Scholar
  • Aleksandra Kostina, Hanna Bjork, Elena Ignatieva, Olga Irtyuga, Vladimir Uspensky, Daria Semenova, Shohreh Maleki, Alexey Tomilin, Olga Moiseeva, Anders Franco-Cereceda, Mikhail Gordeev, Giuseppe Faggian, Anna Kostareva, Per Eriksson, and Anna Malashicheva, “Notch, BMP and WNT/β-catenin network is impaired in endothelial cells of the patients with thoracic aortic aneurysm,” Atherosclerosis Supplements, 2018. View at Publisher · View at Google Scholar
  • Anna Chiarini, Elisabetta Trabetti, Francesco Onorati, Giuseppe Faggian, Ubaldo Armato, Ilaria Dal Pra, Maddalena Marconi, Alessandra Pasquali, Cristina Patuzzo, Anna Malashichev, Olga Irtyega, and Pier F Pignatti, “Studies on sporadic non-syndromic thoracic aortic aneurysms: 1. Deregulation of Jagged/Notch 1 homeostasis and selection of synthetic/secretor phenotype smooth muscle cells,” European Journal of Preventive Cardiology, vol. 25, no. 1, pp. 42–50, 2018. View at Publisher · View at Google Scholar
  • Fernando Rodríguez-Pascual, Francisco Laurindo, Thayna Meirelles, Francesc Jiménez-Altayó, Enric Condom, Marta Sitges, Joaquim Ros, Isabel Fabregat, Eva Crosas-Molist, Aleksandra Mas-Stachurska, Ana-Maria Siegert, Fabio Bonorino, Laura Barberà, Katrin Schröder, Gustavo Egea, M. Alba Sorolla, Darya Gorbenko del Blanco, Carolina García, and Judit López-Luque, “Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm,” Free Radical Biology and Medicine, vol. 118, pp. 44–58, 2018. View at Publisher · View at Google Scholar
  • Iris Zeller, Stefan Blunder, Andreas Zierer, David Bernhard, Barbara Messner, Günther Laufer, Bernhard Scharinger, and Christian Doppler, “Targeted gene expression analyses and immunohistology suggest a pro-proliferative state in tricuspid aortic valve-, and senescence and viral infections in bicuspid aortic valve-associated thoracic aortic aneurysms,” Atherosclerosis, vol. 271, pp. 111–119, 2018. View at Publisher · View at Google Scholar
  • Bengt-Olof Nilsson, Amalia Forte, Marisa De Feo, Lo Persson, Ciro Bancone, Marilena Cipollaro, Alessandro Della Corte, Mario Grossi, and Per Hellstrand, “Polyamine concentration is increased in thoracic ascending aorta of patients with bicuspid aortic valve,” Heart and Vessels, vol. 33, no. 3, pp. 327–339, 2018. View at Publisher · View at Google Scholar
  • Hanna M. Björck, Lei Du, Silvia Pulignani, Valentina Paloschi, Karin Lundströmer, Alexandra S. Kostina, Cecilia Österholm, Anna Malashicheva, Anna Kostareva, Arturo Evangelista, Gisela Teixidó-Tura, Shohreh Maleki, Anders Franco-Cereceda, and Per Eriksson, “Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve,” Scientific Reports, vol. 8, no. 1, 2018. View at Publisher · View at Google Scholar
  • Silviu I. Dumitrescu, Mariana Jinga, Daniel Cochior, Ecaterina Bontas, Irinel Parepa, Daniel Nita, Cristian Gabriel, and Ion C. Ţintoiu, “Endothelial Dysfunction in Aortic Aneurysm,” New Approaches to Aortic Diseases from Valve to Abdominal Bifurcation, pp. 25–39, 2018. View at Publisher · View at Google Scholar
  • Kseniya Perepelina, Polina Klauzen, Anna Kostareva, and Anna Malashicheva, “Tissue-Specific Influence of Lamin A Mutations on Notch Signaling and Osteogenic Phenotype of Primary Human Mesenchymal Cells,” Cells, vol. 8, no. 3, pp. 266, 2019. View at Publisher · View at Google Scholar
  • Arkady Rutkovskiy, Maria Lund, Tanja Saman Siamansour, Trine Marita Reine, Svein Olav Kolset, Kristin Larsen Sand, Elena Ignatieva, Mikhail L Gordeev, Kåre-Olav Stensløkken, Guro Valen, Jarle Vaage, and Anna Malashicheva, “Mechanical stress alters the expression of calcification-related genes in vascular interstitial and endothelial cells,” Interactive CardioVascular and Thoracic Surgery, 2019. View at Publisher · View at Google Scholar