Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana

Table 3

Logistic regression models of peripheral arterial disease and vascular growth factors.

	Crude OR (95% CI)		Adjusted OR 95% CI
Ang-1	0.91 (0.56–0.99)	0.024	0.84 (0.42–1.48)	0.096
Ang-2	1.56 (0.89–3.06)	0.532	1.92 (0.76–3.52)	0.427
VEGF	1.29 (1.07–1.97)	0.037	1.14 (0.92–2.13)	0.104
Ang-1/2	1.08 (0.66–1.84)	0.347	1.21 (0.51–2.41)	0.625

for age, gender, alcohol status, previous cigarette smoking, BMI, waist-hip ratio, diabetes, hypertension, and total cholesterol. All the angiogenic growth factors were logarithmically transformed to improve skewness before analysis. Ang-1: angiopoietin 1; Ang-2: angiopoietin 2; VEGF: vascular-endothelial growth factor; Ang-1/2: angiopoietin 1/angiopoietin 2 ratio.