Circulating Angiogenic Growth Factors in Diabetes Patients with Peripheral Arterial Disease and Exertional Leg Pain in Ghana

Table 4

Logistic regression models of leg pains and vascular growth factors.

	Crude OR (95% CI)		Adjusted OR 95% CI
Ang-1	1.11 (1.02–2.26)	0.048	1.09 (0.59–2.01)	0.479
Ang-2	3.05 (1.14–8.94)	0.012	2.08 (1.08–6.41)	0.036
VEGF	1.48 (0.35–10.25)	0.747	0.69 (0.41–9.53)	0.78
Ang-1/2	1.16 (0.27–2.39)	0.239	0.8 (0.32–1.99)	0.631

for age, gender, alcohol status, previous cigarette smoking, BMI, waist-hip ratio, diabetes, hypertension, and total cholesterol. All the angiogenic growth factors were logarithmically transformed to improve skewness before analysis. Ang-1: angiopoietin 1; Ang-2: angiopoietin 2; VEGF: vascular-endothelial growth factor; Ang-1/2: angiopoietin 1/angiopoietin 2 ratio.