Research Article
Clinical Arterial Peripheral Vascular Pathology Does Not Impact Short- or Long-Term Survival after Transcatheter Aortic Valve Replacement
| | | Vascular Pathology (n=147) | Control (n=195) | P-value |
| | Age | 80.6 (7.55) | 78.1 (9.76) | .011 |
| | Male sex | 67 (99) | 47 (92) | <.001 |
| | BMI | 29.7 (6.04) | 31.0 (6.34) | .344 |
| | Caucasian race | 99 (145) | 99 (194) | 1.000 |
| | EuroSCORE () | 10.91 (6.90) | 6.84 (5.29) | <.001 |
| | STS Risk Score () | 8.35 (4.67) | 5.48 (3.03) | <.001 |
| | Preprocedural HTN | 88 (129) | 88 (172) | 1.000 |
| | Preprocedural CAD | 87 (128) | 63 (123) | <.001 |
| | Baseline Ejection Fraction <40 | 17 (25) | 12 (24) | .275 |
| | Preprocedural NYHA | 45 (66) | 44 (85) | .827 | | Class III OR IV Symptoms | | | |
| | Preprocedural DM | 36 (53) | 35 (68) | .820 |
| | Prior Stroke/TIA | 16 (24) | 8 (15) | .016 |
| | Preprocedural Atrial Fibrillation | 35 (52) | 27 (52) | .097 |
| | Preprocedural Serum Creatinine (mg/dL) | 1.46 (1.14) | 1.11 (0.46) | <.001 |
| | Preprocedural eGFR < 60 mL/min | 55 (81) | 43 (83) | .022 |
| | Preprocedural Dyslipidemia | 100 (147) | 83 (162) | <.001 |
| | Preprocedural AAA | 26 (38) | - | - |
| | Preprocedural Carotid Artery | 63 (93) | - | - | | Stenosis >50 or Prior CEA | | | |
| | Preprocedural Symptomatic PAD | 64 (94) | - | - |
| | Prior CABG | 35 (52) | 23 (44) | .011 |
| | Prior PCI | 44 (65) | 31 (60) | .013 |
| | Prior Permanent Pacemaker | 13 (19) | 11 (22) | .737 |
| | Prior Aortic Valvuloplasty | 19 (28) | 16 (31) | .472 |
| | Cardiovascular Pharmacology | | | |
| | ACE inhibitor | 34 (50) | 31 (61) | .641 |
| | Angiotensin II receptor blocker | 14 (20) | 21 (40) | .114 |
| | Beta blocker () | 78 (114) | 71 (138) | .174 |
| | Calcium channel blocker | 26 (38) | 30 (59) | .398 |
| | Thiazide diuretic | 19 (28) | 22 (43) | .590 |
| | Loop diuretic | 52 (77) | 47 (92) | .382 |
| | Spironolactone | 3 (4) | 4 (8) | .565 |
| | Statin | 77 (113) | 66 (128) | .031 |
| | Aspirin | 84 (123) | 70 (136) | .003 |
| | Dual Antiplatelet Therapy | 36 (53) | 22 (42) | .003 |
| | Any anticoagulant | 28 (41) | 23 (45) | .317 |
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Values are mean (standard deviation) or % (n).
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