Research Article

Appropriateness of Pharmacologic Prophylaxis against Deep Vein Thrombosis in Medical Wards of an Ethiopian Referral Hospital

Table 5

Factors associated with inappropriateness of thromboprophylaxis.

VariableCategoryInappropriateness of thromboprophylaxisCOR (95% CI)AOR
(95% CI)
P value
AppropriateInappropriate

SexFemale69 (63.9%)39 (36.1%)1.565 (0.862-2.841)1.061 (0.464- 2.430)0.888
Male72 (73.5%)26 (26.5%)1.001.00

Age18-4077 (72.0%)30 (28.0%)0.487 (0.223-1.064)0.354 (0.071- 1.757)0.204
41-6444 (69.8%)19 (30.2%)0.540 (0.231-1.262)0.215 (0.042- 1.111)0.067
>=6520 (55.6%)16 (44.4%)1.001.00

CNS disorderNo127(69.8%)55 (30.2%)0.606 (0.254-1.449)0.910 (0.254- 3.259)0.884
Yes14 (58.3%)10 (41.7%)1.001.00

Infectious diseaseNo43 (60.6%)28 (39.4%)1.725 (0.939-3.168)1.053 (0.459- 2.415)0.903
Yes98 (72.6%)37 (27.4%)1,001.00

Critically illNo113(85.0%)20 (15.0%)0.110 (0.056-0.215)0.766 (0.272- 2.160)0.615
Yes28 (38.4%)45 (61.6%)1.001.00

Reduced MobilityNo117(72.2%)45 (27.8%)0.462 (0.232-0.916)2.373 (0.919- 6.131)0.074
Yes24 (54.5%)20 (45.5%)1.001.00

Age>=70 yearsNo127 (69.0%)57 (31.0%)0.785 (0.312-1.977)6.173 (0.960-39.679)0.055
Yes14 (63.6%)8 (36.4%)1.001.00

Heart or Respiratory FailureNo109 (71.2%)44 (28.8%)0.615 (0.320-1.181)1.175 (0.468- 2.952)0.731
Yes32 (60.4%)21 (39.6%)1.001.00

Risk of the patient for thromboembolismHigh40 (40.8%)58 (59.2%)20.921 (8.805- 49.713)31.67(8.518-117.72)0.000
Low101 (93.5%)7 (6.5%)1.001.00

Thrombocytopenia OR coagulopathyNo117 (64.6%)64 (35.4%)13.128 (1.736- 99.307)25.17 (2.862- 221.30)0.004
Yes24 (96.0%)1 (4.0%)1.001.00

COR: Crude Odds Ratio; AOR: Adjusted Odds Ratio; CI: Confidence Interval.