(a)
(b)
Figure 2: A model of atherogenesis/restenosis, showing differences caused by physiologic arterial wall shear (a) and low (proatherogenic/prorestenotic) wall shear (b) in upregulation of endothelial-cell genes and proteins that are atheroprotective/antirestenotic or atherogenic/restenotic. Adapted from Malek et al. with permission [30].