International Journal of Vascular Medicine / 2020 / Article / Tab 1

Clinical Study

Automatic Continuous CRT Optimization to Improve Hemodynamic Response: An Italian Single-Center Experience

Table 1

Baseline characteristics of heart failure patients, overall and by etiology (ischemic versus nonischemic).

Baseline characteristicsOverallIschemicNonischemic value
Patients ()31 (100%)20 (65%)11 (35%)

Demographics
 Men19 (61%)14 (70%)5 (45%)0.18
 Age (years)0.37
 Weight (kg)0.49
Baseline NYHA class
 NYHA0.14
 Class II6 (19%)5 (25%)1 (9%)<0.001
 Class III25 (81%)15 (75%)10 (91%)
Comorbidities/CV risk factors
 Diabetes9 (29%)9 (45%)0 (0%)<0.01
 Systemic hypertension11 (35%)7 (35%)4 (36%)0.94
 Renal dysfunction1 (3%)1 (5%)0 (0%)0.45
 COPD4 (13%)3 (15%)1 (9%)0.63
ECG findings
 QRS duration (ms)0.47
 LBBB morphology20 (65%)12 (60%)8 (73%)0.012
 Non-LBBB morphology11 (35%)8 (40%)3 (27%)
 SBP (mmHg)0.23
 DBP (mmHg)0.43
Echocardiographic findings
 LV ejection fraction (%)%%%0.27
 ≤25%10 (32%)8 (40%)2 (18%)0.21
 >25%21 (68%)12 (60%)9 (82%)
 Left atrial diameter (mm)0.39
 LVEDV (mL)0.06
Medical therapy
 Beta-blockers31 (100%)20 (100%)11 (100%)
 Diuretics31 (100%)20 (100%)11 (100%)
 Aldosterone antagonist31 (100%)20 (100%)11 (100%)
 ACE inhibitor or ARNI31 (100%)20 (100%)11 (100%)

Data are presented as number and percentage or . Valsartan/sacubitril. Abbreviations: ACE: angiotensin-converting enzyme; ARNI: angiotensin receptor-neprilysin inhibitor; COPD: chronic obstructive pulmonary disease; CV: cardiovascular; DBP: diastolic blood pressure; ECG: electrocardiogram; LBBB: left bundle-branch block; LV: left ventricular; LVEDV: left ventricular end-diastolic volume; NYHA: New York Heart Association; SBP: systolic blood pressure.

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